Rizatriptan combined with rofecoxib vs. rizatriptan for the acute treatment of migraine: an open label pilot study.

Author: BarbosaJ S, KrymchantowskiA V

Paper Details 
Original Abstract of the Article :
Rizatriptan is an effective and fast acting drug for the acute treatment of migraine. As with any other acute treatment for migraine, headache recurrence may occur in up to one-third of responders. Combination with non-steroidal anti-inflammatory drugs (NSAIDs) seems to reduce the incidence of heada...See full text at original site
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引用元:
https://doi.org/10.1046/j.1468-2982.2002.00369.x

データ提供:米国国立医学図書館(NLM)

Combating Migraine: A New Combination Therapy

Migraine, a debilitating headache disorder, can significantly impact quality of life. This study, like a skilled physician seeking to alleviate suffering, explores the effectiveness of combining rizatriptan, a fast-acting migraine medication, with rofecoxib, a non-steroidal anti-inflammatory drug (NSAID), in treating acute migraine attacks. The research uses an open-label pilot study design to examine the potential benefits of this combination therapy.

A Synergistic Approach

The study found that the combination of rizatriptan and rofecoxib significantly reduced the recurrence rate of migraine attacks compared to rizatriptan alone. The research also confirmed that the combination therapy was well-tolerated, with no significant differences in side effects compared to rizatriptan alone. These findings, like a camel caravan pooling its resources, suggest that combining different medications could offer a synergistic approach to migraine management, potentially leading to more effective pain relief and fewer recurrences.

Managing Migraine Effectively

This study highlights the potential of combination therapy in managing migraine. The research suggests that combining rizatriptan with rofecoxib could offer a more effective and sustainable approach to migraine management, potentially reducing the frequency and severity of migraine attacks. This study provides valuable insights for guiding clinical decision-making and ultimately improving the quality of life for individuals suffering from migraine.

Dr. Camel's Conclusion

Navigating the world of migraine, like a camel traversing a scorching desert, requires a reliable and effective treatment plan. This study, like a well-stocked caravan, explores the benefits of combining rizatriptan with rofecoxib. The research suggests that this combination therapy could offer a more effective and sustainable approach to migraine management, potentially reducing the burden of this debilitating condition. By utilizing this knowledge, we can help individuals suffering from migraine find a path towards a brighter and pain-free future.

Date :
  1. Date Completed 2002-09-10
  2. Date Revised 2017-02-14
Further Info :

Pubmed ID

12100094

DOI: Digital Object Identifier

10.1046/j.1468-2982.2002.00369.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

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