Options for pharmacological management of obesity in patients treated with atypical antipsychotics.

Author: SandersT A B, TaylorD, WernekeU

Paper Details 
Original Abstract of the Article :
Obesity is associated with considerable morbidity and decreased life expectancy. Weight gain is a commonly encountered problem associated with antipsychotic treatment. We reviewed the literature regarding the mechanisms of weight gain in response to these agents and eight substances implicated as po...See full text at original site
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引用元:
https://doi.org/10.1097/00004850-200207000-00001

データ提供:米国国立医学図書館(NLM)

Weight Gain: A Common Side Effect of Atypical Antipsychotics

This study examines the complex relationship between atypical antipsychotic medications and weight gain, a common side effect that can significantly impact the health and well-being of patients. The researchers reviewed the literature on the mechanisms of weight gain associated with antipsychotic treatment, exploring the involvement of various neurotransmitters and hormonal factors. The study also investigated the potential of eight different medications, including orlistat, sibutramine, fluoxetine, topiramate, amantadine, nizatidine, cimetidine, and metformin, for preventing or treating weight gain in patients taking atypical antipsychotics. The review found that limited evidence supports the use of pharmacological interventions for weight management in patients taking antipsychotics, concluding that individualized approaches are often more effective.

Managing Weight Gain: A Balancing Act for Antipsychotic Patients

The study highlights the challenges of managing weight gain in patients taking atypical antipsychotics. While the mechanisms underlying weight gain are complex, the review suggests that a combination of lifestyle modifications and, in some cases, targeted medication interventions can be helpful.

Finding the Right Balance: A Collaborative Approach to Weight Management

This study emphasizes the importance of collaboration between healthcare providers and patients in managing weight gain associated with antipsychotic medications. Finding the right balance between medication management, lifestyle changes, and potential pharmacological interventions is crucial for maximizing the benefits of treatment while minimizing the risks of weight gain.

Dr. Camel's Conclusion

This study is like a camel caravan navigating a treacherous desert, seeking the best path to manage weight gain in patients taking atypical antipsychotics. The research sheds light on the complex interplay of factors that contribute to weight gain and highlights the need for a multi-pronged approach to minimize its impact on patient health.

Date :
  1. Date Completed 2002-12-12
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

12131598

DOI: Digital Object Identifier

10.1097/00004850-200207000-00001

Related Literature

SNS
PICO Info
in preparation
Languages

English

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