Hyperlipidaemia a risk factor for femoral head osteonecrosis (Legg-Calv -Perthes-like disease) in children with AIDS: case report.

Author: Aguiar De AragãoPaula, AquinoMaria Zilda, LemosRenata B P, Souza MarquesHeloisa Helena

Paper Details 
Original Abstract of the Article :
Although treatment of children infected with HIV with protease inhibitors has improved the survival of these patients, various adverse side effects have been reported, including metabolic abnormalities, such as hyperlipidaemia. We describe a case of hip osteonecrosis in an adolescent with AIDS who w...See full text at original site
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引用元:
https://doi.org/10.1590/s1413-86702002000300008

データ提供:米国国立医学図書館(NLM)

Hyperlipidemia: A Hidden Sandstorm in Children with AIDS

This case report explores a potential link between hyperlipidemia and femoral head osteonecrosis (Legg-Calvé-Perthes-like disease) in children with AIDS. It's like a hidden sandstorm, a seemingly unrelated factor that can have a significant impact on health. The researchers describe a case of a young boy with AIDS who developed osteonecrosis, a condition that affects the blood supply to the hip joint. The boy was being treated with protease inhibitors, which are commonly used to treat HIV infection, and had developed high triglyceride levels, a hallmark of hyperlipidemia. The researchers suggest that hyperlipidemia, often a side effect of protease inhibitors, could be a contributing factor to osteonecrosis in children with AIDS.

A Warning in the Desert

This case report serves as a warning, highlighting the potential risks of hyperlipidemia in children with AIDS. It's like a mirage, a seemingly harmless factor that could lead to serious complications. This research emphasizes the need for careful monitoring of lipid levels in children with AIDS who are receiving protease inhibitor therapy. Early detection and treatment of hyperlipidemia could potentially reduce the risk of osteonecrosis and other complications.

Navigating the Desert of HIV Treatment

This research underscores the importance of careful monitoring and management of side effects in patients with HIV infection. It's like a long and arduous journey across a vast desert, where every step must be carefully considered. Understanding the potential risks associated with HIV treatment is crucial for ensuring the long-term health and well-being of patients.

Dr.Camel's Conclusion

This case report, like a footprint in the sand, reminds us of the importance of careful monitoring in HIV treatment. The potential link between hyperlipidemia and osteonecrosis underscores the need for comprehensive management and the importance of recognizing potential complications, even those seemingly unrelated to the primary condition.
Date :
  1. Date Completed 2003-01-22
  2. Date Revised 2019-10-25
Further Info :

Pubmed ID

12144752

DOI: Digital Object Identifier

10.1590/s1413-86702002000300008

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