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Amitriptyline versus amitriptyline combined with fluoxetine in the preventative treatment of transformed migraine: a double-blind study.

Author: AlvesLuiz Anastácio, BarbosaJackeline Soraya, KrymchantowskiAbouch Valenty, SilvaMarcus Tulius

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effectiveness and side effects of combining amitriptyline and fluoxetine compared to using amitriptyline alone for treating chronic daily headaches related to transformed migraine, a type of headache often associated with mood disorders.
Paper Details　
Original Abstract of the Article :
Antidepressants are often used to treat chronic daily headache disorders such as transformed migraine, in part because of the high prevalence of associated mood disorder. We conducted this study to evaluate the efficacy and tolerability of combined treatment with amitriptyline and fluoxetine compare...See full text at original site
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引用元：
https://doi.org/10.1046/j.1526-4610.2002.02125.x

データ提供：米国国立医学図書館（NLM）

A Balancing Act: Amitriptyline and Fluoxetine for Transformed Migraine

This study investigates the efficacy of combining amitriptyline and fluoxetine for the preventative treatment of transformed migraine. The authors conducted a double-blind study to compare the effectiveness of combined treatment with amitriptyline alone. Their findings suggest that combining amitriptyline with fluoxetine may offer a more effective and tolerable treatment option for chronic daily headaches associated with transformed migraine.

The Desert of Chronic Pain: Finding Relief from Transformed Migraine

This study explores the complex world of chronic daily headaches and transformed migraine. The authors investigate the potential benefits of combining amitriptyline and fluoxetine as a preventative treatment. Imagine a vast and relentless desert of pain. This study explores a new pathway that may offer a more effective and tolerable oasis of relief for those suffering from transformed migraine.

The Oasis of Combination Therapy: Finding a Balanced Approach

This research highlights the potential benefits of combining different medications in treating transformed migraine. It's like discovering a new oasis in the desert of chronic pain, where a combination of healing elements offers a more effective and balanced approach to managing the symptoms.

Dr.Camel's Conclusion

This study suggests that combining amitriptyline and fluoxetine may offer a more effective and tolerable treatment option for transformed migraine. It's like finding a new oasis in the vast desert of chronic pain, where a combination of therapies offers a more balanced and effective approach to managing the symptoms.

Date :
  1. Date Completed 2002-11-15
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

12167139

DOI: Digital Object Identifier

10.1046/j.1526-4610.2002.02125.x

Related Literature

Article Analysis
・Effective treatment of migraine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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