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Apoptosis induction by the Therien and vaccine RA27/3 strains of rubella virus causes depletion of oligodendrocytes from rat neural cell cultures.

Author: AtkinsGregory J, DomeganLisa M

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Rubella virus (RV) can cause cell death in oligodendrocytes, a type of brain cell, through a process called apoptosis. This finding may help explain how RV causes neurological damage.
Paper Details　
Original Abstract of the Article :
The induction of cell death by the Therien strain of rubella virus (RVT), and the vaccine RA27/3 strain, was investigated in mixed glial cell cultures derived from the rat CNS. Cell death induction in Vero and rat glial cells by RVT and RA27/3 was dependent on virus replication. In both cell types a...See full text at original site
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引用元：
https://doi.org/10.1099/0022-1317-83-9-2135

データ提供：米国国立医学図書館（NLM）
in preparation
Date :
  1. Date Completed 2002-09-27
  2. Date Revised 2020-02-19
Further Info :

Pubmed ID

12185266

DOI: Digital Object Identifier

10.1099/0022-1317-83-9-2135

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Article Analysis
・Causes of rubella
SNS
PICO Info
in preparation
Languages

English

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