Meta-analyses of therapies for postmenopausal osteoporosis. VIII: Meta-analysis of the efficacy of vitamin D treatment in preventing osteoporosis in postmenopausal women.

Author: , AdachiJonathan, CranneyAnn, GillespieWilliam, GreenwoodCarol, GuyattGordon, JosseRobert, PapadimitropoulosEmmanuel, SheaBeverley, TugwellPeter, WeaverBruce, WellsGeorge, ZytarukNicole

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To review the effect of vitamin D on bone density and fractures in postmenopausal women. DATA SOURCE: We searched MEDLINE and EMBASE from 1966 to 1999 and examined citations of relevant articles and proceedings of international meetings. We contacted osteoporosis investigators and primar...See full text at original site
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引用元:
https://doi.org/10.1210/er.2001-8002

データ提供:米国国立医学図書館(NLM)

Vitamin D: A Powerful Ally in the Fight Against Postmenopausal Osteoporosis

Osteoporosis, a condition characterized by weakened bones, is a significant public health concern, particularly among postmenopausal women. This study investigates the role of vitamin D in preventing osteoporosis and related fractures in this population. The researchers conducted a meta-analysis of 25 randomized controlled trials examining the effects of vitamin D supplementation on bone density and fracture incidence in postmenopausal women.

The meta-analysis revealed that vitamin D supplementation significantly reduced the incidence of vertebral fractures and showed a trend toward reduced nonvertebral fractures. The researchers also found that hydroxylated vitamin D, a more active form of vitamin D, had a greater impact on bone density compared to standard vitamin D. The study also noted an increased risk of medication discontinuation due to side effects or abnormal laboratory results with vitamin D supplementation, suggesting the need for careful monitoring.

The Importance of Vitamin D: A Foundation for Bone Health

The findings from this study highlight the crucial role of vitamin D in maintaining bone health, particularly for postmenopausal women. Vitamin D supplementation can effectively reduce the risk of fractures, a major concern for this population. However, careful monitoring is essential to manage potential side effects and ensure the safe and effective use of vitamin D.

Building Strong Bones: A Comprehensive Approach to Bone Health

This study emphasizes the importance of a holistic approach to bone health, including adequate vitamin D intake, calcium supplementation, and regular exercise. By understanding the role of vitamin D and other factors influencing bone health, individuals can make informed choices to minimize their risk of osteoporosis and related fractures.

Dr. Camel's Conclusion

This study is like a desert oasis, offering a vital source of hydration for our bones. Vitamin D supplementation can effectively reduce the risk of fractures, especially for postmenopausal women. But remember, like a desert oasis, this resource needs to be managed carefully to maximize its benefits and avoid any unwanted side effects. By taking a comprehensive approach to bone health, we can build strong bones and minimize our risk of osteoporosis.

Date :
  1. Date Completed 2003-02-07
  2. Date Revised 2022-03-16
Further Info :

Pubmed ID

12202471

DOI: Digital Object Identifier

10.1210/er.2001-8002

Related Literature

SNS
PICO Info
in preparation
Languages

English

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