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Meta-analyses of therapies for postmenopausal osteoporosis. VIII: Meta-analysis of the efficacy of vitamin D treatment in preventing osteoporosis in postmenopausal women.
Author: , AdachiJonathan, CranneyAnn, GillespieWilliam, GreenwoodCarol, GuyattGordon, JosseRobert, PapadimitropoulosEmmanuel, SheaBeverley, TugwellPeter, WeaverBruce, WellsGeorge, ZytarukNicole
Original Abstract of the Article :
OBJECTIVE: To review the effect of vitamin D on bone density and fractures in postmenopausal women. DATA SOURCE: We searched MEDLINE and EMBASE from 1966 to 1999 and examined citations of relevant articles and proceedings of international meetings. We contacted osteoporosis investigators and primar...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1210/er.2001-8002
データ提供:米国国立医学図書館(NLM)
Vitamin D: A Powerful Ally in the Fight Against Postmenopausal Osteoporosis
Osteoporosis, a condition characterized by weakened bones, is a significant public health concern, particularly among postmenopausal women. This study investigates the role of vitamin D in preventing osteoporosis and related fractures in this population. The researchers conducted a meta-analysis of 25 randomized controlled trials examining the effects of vitamin D supplementation on bone density and fracture incidence in postmenopausal women.
The meta-analysis revealed that vitamin D supplementation significantly reduced the incidence of vertebral fractures and showed a trend toward reduced nonvertebral fractures. The researchers also found that hydroxylated vitamin D, a more active form of vitamin D, had a greater impact on bone density compared to standard vitamin D. The study also noted an increased risk of medication discontinuation due to side effects or abnormal laboratory results with vitamin D supplementation, suggesting the need for careful monitoring.
The Importance of Vitamin D: A Foundation for Bone Health
The findings from this study highlight the crucial role of vitamin D in maintaining bone health, particularly for postmenopausal women. Vitamin D supplementation can effectively reduce the risk of fractures, a major concern for this population. However, careful monitoring is essential to manage potential side effects and ensure the safe and effective use of vitamin D.
Building Strong Bones: A Comprehensive Approach to Bone Health
This study emphasizes the importance of a holistic approach to bone health, including adequate vitamin D intake, calcium supplementation, and regular exercise. By understanding the role of vitamin D and other factors influencing bone health, individuals can make informed choices to minimize their risk of osteoporosis and related fractures.
Dr. Camel's Conclusion
This study is like a desert oasis, offering a vital source of hydration for our bones. Vitamin D supplementation can effectively reduce the risk of fractures, especially for postmenopausal women. But remember, like a desert oasis, this resource needs to be managed carefully to maximize its benefits and avoid any unwanted side effects. By taking a comprehensive approach to bone health, we can build strong bones and minimize our risk of osteoporosis.
Date :
- Date Completed 2003-02-07
- Date Revised 2022-03-16
Further Info :
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