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Randomised controlled trial of nitrofurantoin versus placebo in the treatment of uncomplicated urinary tract infection in adult women.

Author: ChristiaensT C M, De MaeseneerJ M, De MeyereM, HeytensS, PeersmanW, VerschraegenG

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Nitrofurantoin is significantly more effective than placebo in achieving bacteriological cure and symptomatic relief in women with bacteriologically proven UTI.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Urinary tract infections (UTIs) are very common and have been treated with apparent success with antimicrobials for many years. However, there is a paucity of placebo-controlled clinical trials. AIM: To measure the symptomatic and bacteriological short-term effect of nitrofurantoin trea...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1314413/

データ提供：米国国立医学図書館（NLM）

Nitrofurantoin: A Proven Path Through the Desert of UTIs

This research examines the efficacy of nitrofurantoin, an antibiotic, in treating uncomplicated urinary tract infections (UTIs) in adult women. The study employs a randomized, placebo-controlled design to compare the effects of nitrofurantoin to placebo in terms of both symptomatic and bacteriological outcomes. The researchers meticulously analyze the data, seeking to determine the effectiveness of nitrofurantoin in resolving UTI symptoms and eradicating bacteria.

A Proven Remedy: Nitrofurantoin's Effectiveness Against UTIs

This research provides strong evidence for the effectiveness of nitrofurantoin in treating uncomplicated UTIs. The study demonstrates that nitrofurantoin is significantly more effective than placebo in achieving both symptomatic relief and bacteriological cure, particularly within three days of treatment. These findings reinforce the role of nitrofurantoin as a valuable therapeutic option for managing UTIs.

The Oasis of Relief: Nitrofurantoin and UTI Management

This research underscores the importance of timely and effective treatment for UTIs. Just as a desert traveler seeks out an oasis to replenish their resources, individuals experiencing UTI symptoms should seek medical attention promptly. Nitrofurantoin, a proven antibiotic, offers a reliable path to relief from UTI symptoms and can help prevent complications.

Dr. Camel's Conclusion

This research provides compelling evidence for the effectiveness of nitrofurantoin in treating uncomplicated UTIs. The study confirms its superiority over placebo in achieving both symptomatic relief and bacteriological cure. However, it's important to remember that antibiotic resistance is a growing concern. Always consult with a healthcare professional to determine the appropriate treatment for your UTI and to ensure safe and effective management of this common condition.

Date :
  1. Date Completed 2002-10-16
  2. Date Revised 2022-03-30
Further Info :

Pubmed ID

12236276

DOI: Digital Object Identifier

PMC1314413

Related Literature

Article Analysis
・Effective treatment of urinary tract infections
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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