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A comparative trial of two retinoids commonly used in the treatment of acne vulgaris.

Author: BergerR S, GrossmanR M, JorizzoJ L, KimY H, MartinA G, NighlandM, NyiradyJ, PandyaA G, SchulzK K, StraussJ S

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tretinoin gel microsphere 0.1% and adapalene gel 0.1% demonstrate comparable efficacy in treating acne vulgaris, but tretinoin gel microsphere may have a faster onset of action in reducing comedones. While both treatments are effective, tretinoin gel microsphere is associated with higher incidences of dryness and peeling.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Topical retinoids are highly effective treatments for acne vulgaris. The various formulations and concentrations available allow physicians to tailor therapies to individual patient's needs and minimize the cutaneous irritation that is often observed with the use of these drugs. OBJECTI...See full text at original site
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引用元：
https://doi.org/10.1080/09546630152607880

データ提供：米国国立医学図書館（NLM）

Tretinoin and Adapalene: A Head-to-Head Comparison for Acne Vulgaris

Acne vulgaris, a common skin condition that affects millions, can be a frustrating and often embarrassing experience. This research, like a meticulous desert botanist examining different plants, compares the effectiveness and safety of two commonly used topical retinoids, tretinoin and adapalene, in treating acne vulgaris. The study, like a carefully controlled experiment in a desert laboratory, evaluates the efficacy of these medications in reducing acne lesions and assesses their potential side effects.

Similar Efficacy with Subtle Differences

The findings suggest that both tretinoin and adapalene are effective in treating acne vulgaris, demonstrating similar overall efficacy in reducing acne lesions. It’s like discovering two different plants offering similar therapeutic benefits in the desert. The study highlights a slight difference in the speed of action, with tretinoin potentially leading to a faster reduction in comedones, or blackheads.

Navigating the Desert of Acne Treatment Options

This research provides valuable information for individuals seeking effective treatment for acne vulgaris. It’s like discovering a map to navigate the diverse landscape of acne treatment options. The findings suggest that both tretinoin and adapalene can be effective, with tretinoin potentially offering a faster onset of action.

Dr. Camel’s Conclusion

This research provides a comprehensive comparison of two commonly used topical retinoids for acne vulgaris. It highlights the potential of both tretinoin and adapalene as effective treatment options, offering valuable information for individuals seeking a solution for acne. It’s a reminder that the desert of acne treatment options can be vast, but with careful research, we can find the right path to clear skin.
Date :
  1. Date Completed 2002-10-08
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

12243706

DOI: Digital Object Identifier

10.1080/09546630152607880

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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