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Amoxapine shows atypical antipsychotic effects in patients with schizophrenia: results from a prospective open-label study.

Author: ApiquianRogelio, FresanAna, KapurShitij, LoyzagaCristina, NicoliniHumberto, UlloaElena

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Amoxapine, marketed as an antidepressant, shares similarities with atypical antipsychotics in terms of receptor occupancy and effects in pre-clinical models. This study investigated the antipsychotic and side effect profile of amoxapine in acutely psychotic patients with schizophrenia, suggesting that amoxapine might possess atypical antipsychotic effects.
Paper Details　
Original Abstract of the Article :
Amoxapine is marketed as an antidepressant. However, its receptor occupancy, in vitro and in vivo, and its effects in pre-clinical models are very similar to atypical antipsychotics. To examine if this leads to an atypical antipsychotic effect in the clinical context, the authors examined the antips...See full text at original site
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引用元：
https://doi.org/10.1016/s0920-9964(01)00342-5

データ提供：米国国立医学図書館（NLM）

Amoxapine – A Potential Atypical Antipsychotic

This research delves into the complex landscape of schizophrenia treatment, exploring the potential of amoxapine, a drug traditionally used as an antidepressant, as an atypical antipsychotic. The study, a prospective open-label study, examines the antipsychotic and side-effect profile of amoxapine in patients with schizophrenia. The findings suggest that amoxapine exhibits atypical antipsychotic effects, offering a potential alternative treatment option for individuals with schizophrenia.

Amoxapine – A Potential New Path in Antipsychotic Treatment

The study reveals a promising finding – amoxapine demonstrates atypical antipsychotic effects, potentially expanding the treatment options available for individuals with schizophrenia. This research, like finding a hidden oasis in the desert, suggests a new avenue for improving treatment outcomes and enhancing the well-being of patients with schizophrenia.

Navigating the Complexities of Schizophrenia Treatment

This research highlights the importance of ongoing research and development in the field of schizophrenia treatment. Finding new and effective treatment options, like navigating a vast desert, requires persistence and dedication to explore new paths and improve patient care. Remember, understanding the complexities of schizophrenia and engaging with your healthcare team can empower you to make informed decisions about your treatment and manage your condition effectively.

Dr.Camel's Conclusion

This research provides a compelling case for exploring the potential of amoxapine as an atypical antipsychotic for individuals with schizophrenia. The study's findings highlight the importance of ongoing research into new treatment options for schizophrenia, potentially leading to improved outcomes and enhancing the quality of life for patients.

Date :
  1. Date Completed 2003-04-09
  2. Date Revised 2019-09-16
Further Info :

Pubmed ID

12413640

DOI: Digital Object Identifier

10.1016/s0920-9964(01)00342-5

Related Literature

Article Analysis
・Side Effects of amoxapine・Effects of amoxapine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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