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Verteporfin therapy of subfoveal choroidal neovascularization in patients with age-related macular degeneration: additional information regarding baseline lesion composition's impact on vision outcomes-TAP report No. 3.

Author: , ArnoldJennifer, BenchabouneMustapha, BlumenkranzMark S, BresslerNeil M, BresslerSusan B, FishGary E, GragoudasEvangelos S, HaoYong, HayesLaurie, KoesterJohn, LewisHilel, ManosKelly, ReavesAl, Schmidt-ErfurthUrsula, SlakterJason S, StrongH Andrew

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

The study explores the relationship between baseline lesion composition and vision outcomes in patients with age-related macular degeneration (AMD) undergoing photodynamic therapy with verteporfin (Visudyne) for subfoveal choroidal neovascularization (CNV).
Paper Details　
Original Abstract of the Article :
To explore how baseline lesion composition influenced vision outcomes in patients with age-related macular degeneration (AMD) undergoing photodynamic therapy with verteporfin (Visudyne) for subfoveal choroidal neovascularization (CNV) in the Treatment of Age-Related Macular Degeneration With Photody...See full text at original site
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引用元：
https://doi.org/10.1001/archopht.120.11.1443

データ提供：米国国立医学図書館（NLM）

Exploring the Impact of Baseline Lesion Composition on Vision Outcomes in Verteporfin Therapy

Age-related macular degeneration (AMD) is a leading cause of vision loss in older adults. Subfoveal choroidal neovascularization (CNV) is a common complication of AMD that can significantly impair vision. This study investigates the impact of baseline lesion composition on vision outcomes in patients with AMD undergoing photodynamic therapy with verteporfin (Visudyne) for subfoveal CNV. The study aimed to determine whether the characteristics of the CNV lesion at the start of treatment influence the effectiveness of verteporfin therapy.

Baseline Lesion Composition: A Potential Indicator of Treatment Success

The study's findings suggest that baseline lesion composition may play a role in determining the success of verteporfin therapy for subfoveal CNV. While more research is needed to fully understand the complex interplay between lesion characteristics and treatment outcomes, this study highlights the importance of considering baseline lesion composition in predicting treatment response and guiding treatment decisions.

Navigating the Landscape of AMD: A Dr. Camel's Perspective

Imagine a desert oasis, where the intricate network of plants and water sustains life. AMD, like a desert sandstorm, can disrupt this delicate balance, affecting the oasis's health and viability. Verteporfin therapy, like a skilled desert engineer, aims to restore balance and functionality to the oasis. This study, like a team of explorers mapping the desert, helps us understand how the initial state of the oasis influences the effectiveness of the engineer's interventions.

Dr. Camel's Conclusion

This study provides valuable insights into the potential impact of baseline lesion composition on vision outcomes in patients with AMD undergoing verteporfin therapy for subfoveal CNV. It underscores the importance of considering lesion characteristics in guiding treatment decisions and optimizing outcomes for patients with AMD. Continued research is needed to further explore the complex relationship between baseline lesion composition and treatment response.

Date :
  1. Date Completed 2002-11-26
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

12427056

DOI: Digital Object Identifier

10.1001/archopht.120.11.1443

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・Effective treatment of macular degeneration
SNS
PICO Info
in preparation
Languages

English

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