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Effects of gender, apolipoprotein E phenotype and cholesterol-lowering by plant stanol esters in children: the STRIP study. Special Turku Coronary Risk Factor Intervention Project.

Author: GyllingH, MarniemiJ, MiettinenT A, Rask-NissiläL, RönnemaaT, SimellO, TammiA, TuominenJ, ViikariJ

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Plant stanol esters reduce serum cholesterol concentration in healthy children irrespective of their gender or apolipoprotein E4 phenotype.
Paper Details　
Original Abstract of the Article :
AIM: To evaluate the effects of gender, apolipoprotein E phenotype and cholesterol absorption and synthesis (estimated as serum plant sterol and cholesterol precursor sterol concentrations) on the cholesterol-lowering effect of plant stanol esters in children. METHODS: Eighty-one healthy, normochol...See full text at original site
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引用元：
https://doi.org/10.1080/080352502320777379

データ提供：米国国立医学図書館（NLM）

Plant Stanol Esters: A Cholesterol-Lowering Strategy for Children

This research investigates the effects of plant stanol esters, a cholesterol-lowering agent, on children's cholesterol levels. The study examines the influence of gender, apolipoprotein E phenotype, and cholesterol metabolism on the cholesterol-lowering effects of plant stanol esters in a group of healthy, normocholesterolaemic 6-year-old children.

Plant Stanol Esters: A Potential Tool for Cholesterol Management in Children

This study provides encouraging evidence for the use of plant stanol esters to lower cholesterol levels in children. The researchers found that plant stanol esters significantly reduced total and low-density lipoprotein (LDL) cholesterol levels in both boys and girls, regardless of their apolipoprotein E phenotype. These findings suggest that plant stanol esters may be a valuable tool for managing cholesterol levels in children, particularly those with a higher risk of developing heart disease.

Heart Health from a Young Age: The Importance of Cholesterol Management

This research highlights the importance of managing cholesterol levels from a young age to promote heart health. The researchers' findings suggest that plant stanol esters, a natural and effective cholesterol-lowering agent, could play a role in preventing heart disease in children. This study underscores the importance of incorporating healthy dietary habits and potentially cholesterol-lowering interventions to promote long-term cardiovascular health.

Dr.Camel's Conclusion

This study is a reminder that taking care of our health is a journey that begins early in life. Just as a camel prepares for a long trek across the desert by ensuring it has sufficient water and supplies, we should strive to develop healthy habits from a young age to ensure a healthy future. The researchers' findings offer hope that plant stanol esters could play a valuable role in promoting heart health and preventing cardiovascular disease in children.

Date :
  1. Date Completed 2003-03-05
  2. Date Revised 2019-08-22
Further Info :

Pubmed ID

12463311

DOI: Digital Object Identifier

10.1080/080352502320777379

Related Literature

Article Analysis
・Effective treatment of cholesterol
SNS
PICO Info
in preparation
Languages

English

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