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The stability of tretinoin in tretinoin gel microsphere 0.1%.

Author: LucasCarmelle, MignonePamela, NyiradyJudit, WisniewskiStephen, YusufMohammed

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Topical tretinoin is a drug used to treat acne. It is more effective and less likely to degrade when it is formulated as a microsphere.
Paper Details　
Original Abstract of the Article :
Topical tretinoin is highly effective and widely used in the treatment of acne vulgaris. In studies to determine the degree of tretinoin photo degradation (isomerization), 2 tretinoin formulations, tretinoin gel microsphere 0.1% and tretinoin gel 0.025%, alone or in combination with erythromycin-ben...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12469785

データ提供：米国国立医学図書館（NLM）

The Stability of Tretinoin in Tretinoin Gel Microsphere 0.1%

This study dives into the world of dermatology, focusing on the stability of tretinoin, a medication commonly used to treat acne. Picture tretinoin as a special desert plant, capable of soothing and healing the skin. The researchers investigated the effects of different formulations on the stability of tretinoin, ensuring that this valuable plant remains potent and effective over time. They discovered that a specific gel microsphere formulation significantly protects tretinoin from degradation, even in the presence of other topical agents. It's like discovering a natural shield that protects a precious desert plant from the harsh elements, allowing it to thrive and flourish.

Tretinoin Stability: Ensuring Effective Treatment

The study revealed that the tretinoin gel microsphere 0.1% formulation offers significantly better protection against photodegradation compared to other formulations. This finding has important implications for ensuring the effectiveness of tretinoin treatment and maximizing its therapeutic benefits. It's like finding a way to cultivate a desert oasis, ensuring that the precious water source remains pure and potent for the benefit of all.

Maintaining Skin Health: Choosing the Right Products

This study emphasizes the importance of choosing the right topical formulations for acne treatment. It highlights the potential for specific formulations to enhance the stability and effectiveness of tretinoin, leading to better therapeutic outcomes. It's like selecting the perfect sand dune to build a temporary shelter, ensuring its stability and protection from the harsh desert environment.

Dr.Camel's Conclusion

This research demonstrates the significance of formulation stability in optimizing tretinoin treatment. It underscores the importance of choosing effective formulations that protect the active ingredient, ensuring optimal therapeutic outcomes. Just as a careful desert traveler selects the right equipment for their journey, choosing the right skincare products can make a significant difference in maintaining healthy and radiant skin.
Date :
  1. Date Completed 2003-05-07
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12469785

DOI: Digital Object Identifier

12469785

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Languages

English

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