Premedication with midazolam in young children: a comparison of four routes of administration.

Author: EfratRachel, EidelmanLeonid A, KatzJacob, KoganAlexander

Paper Details 
Original Abstract of the Article :
BACKGROUND: We undertook a study to determine the effects of four routes of administation on the efficacy of midazolam for premedication. METHODS: In a randomized double-blind study, 119 unmedicated children, ASA I-II, aged 1.5-5 years, who were scheduled for minor elective surgery and who had been...See full text at original site
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引用元:
https://doi.org/10.1046/j.1460-9592.2002.00918.x

データ提供:米国国立医学図書館(NLM)

Midazolam for Premedication in Young Children: Finding the Right Path

Dr. Camel here, exploring the world of [premedication] for young children. Premedication is like preparing a young camel for a long journey across the desert, ensuring a smooth and comfortable experience. This study investigated the effectiveness of midazolam administered through different routes for premedication in young children before minor elective surgery. The research team compared intranasal, oral, rectal, and sublingual routes of administration, assessing sedation levels, anxiety reduction, and mask acceptance for inhalation induction. The study concluded that all four routes of midazolam administration produced satisfactory levels of sedation and anxiolysis, with good mask acceptance for inhalation induction. However, the intranasal route was associated with significant nasal irritation, leading to crying in a majority of children. The study also found that sedation and anxiolysis levels increased with time, reaching their peak at 20 minutes for intranasal administration and 30 minutes for the other routes.

Finding the Right Path

This study provides valuable insights into the efficacy of midazolam administration for premedication in young children. The findings suggest that while all four routes are effective in achieving sedation and anxiolysis, the choice of route should be individualized based on factors such as patient preference and potential side effects. It's like choosing the right path through the desert – considering the terrain, resources, and individual capabilities.

A Smooth Journey for Little Travelers

This research offers valuable information for healthcare providers who administer premedication to young children. By considering the different routes of administration and their associated effects, we can choose the most appropriate approach for each child, ensuring a smoother and more comfortable journey through the desert of medical procedures.

Dr. Camel's Conclusion

This study provides valuable guidance on midazolam administration for premedication in young children. By considering the different routes of administration and their associated effects, we can optimize the premedication experience, ensuring a smoother and more comfortable journey for our little travelers. It's a reminder that even in the vast desert of medical practice, we can find the right paths to ensure optimal care for our patients.

Date :
  1. Date Completed 2003-09-12
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

12472704

DOI: Digital Object Identifier

10.1046/j.1460-9592.2002.00918.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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