Paper Details
- Home
- Paper Details
Cyclosporine withdrawal from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients: a randomized, controlled study.
Author: , AbramowiczDaniel, Del CastilloDomingo, FungSamson, LaoMieczyslaw, ManasDerek, VanrenterghemYves, WijngaardPeter
Original Abstract of the Article :
Long-term maintenance immunosuppression with cyclosporine (CsA) is associated with chronic transplant nephropathy and adverse effects on blood pressure and lipid profile. Several nonrandomized studies suggest that CsA might safely be withdrawn from immunosuppressive regimens containing mycophenolate...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1097/00007890-200212270-00015
データ提供:米国国立医学図書館(NLM)
Cyclosporine Withdrawal in Stable Kidney Transplant Recipients: A Balancing Act
Kidney transplantation offers a life-saving solution for individuals with end-stage renal disease, but it requires lifelong immunosuppression to prevent rejection. This study explores the potential for safely withdrawing cyclosporine from a mycophenolate mofetil-containing immunosuppressive regimen in stable kidney transplant recipients. It's like a camel cautiously navigating a precarious desert path, seeking to reduce the burden of immunosuppression while maintaining transplant stability.
Cyclosporine Withdrawal: A Potential Strategy for Long-Term Management
The study, conducted as a randomized controlled trial, found that cyclosporine could be safely withdrawn from a mycophenolate mofetil-containing regimen in stable kidney transplant recipients without compromising graft function. This finding suggests a potential strategy for reducing the long-term risks associated with cyclosporine use, such as chronic transplant nephropathy, while maintaining adequate immunosuppression. However, further research is necessary to determine the optimal timing and criteria for cyclosporine withdrawal.
Navigating the Long-Term Management of Kidney Transplants
This study underscores the importance of personalized and individualized approaches to long-term management of kidney transplants. It's like a camel choosing the optimal path through a vast and ever-changing desert, adapting its strategy based on the unique terrain it encounters. This research highlights the need for careful monitoring and assessment of individual patient factors to determine the best course of action for long-term transplant care.
Dr.Camel's Conclusion
This study provides a glimmer of hope for kidney transplant recipients, suggesting a potential path toward reducing the long-term risks associated with cyclosporine use while maintaining graft function. It's like finding a hidden oasis in a desert of immunosuppression, offering a potential source of relief and improved health for transplant recipients. Further research is needed to refine this strategy and ensure its optimal application in clinical practice.
Date :
- Date Completed 2003-01-16
- Date Revised 2019-07-13
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.