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Effect of peppermint oil and caraway oil on gastrointestinal motility in healthy volunteers: a pharmacodynamic study using simultaneous determination of gastric and gall-bladder emptying and orocaecal transit time.

Author: GoergK J, SpilkerTh

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Peppermint oil and caraway oil demonstrated a relaxing effect on the gallbladder, with peppermint oil also slowing small intestinal transit. Peppermint oil significantly prolonged the orocaecal transit time, while caraway oil did not.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Although peppermint oil and caraway oil are frequently used in herbal drugs for abdominal discomfort and pain, the pharmacological insights into their effects on the gastrointestinal tract are poor. METHODS: The pharmacodynamic effects of 90 mg peppermint oil (WS 1340) and 50 mg caraway...See full text at original site
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引用元：
https://doi.org/10.1046/j.1365-2036.2003.01421.x

データ提供：米国国立医学図書館（NLM）

Peppermint Oil and Caraway Oil: Exploring Their Effects on Gastrointestinal Motility

Peppermint oil and caraway oil are often used in herbal remedies for digestive discomfort. This study delves into the effects of these oils on the gastrointestinal tract, specifically their impact on the motility of the stomach, gallbladder, and small intestine. The researchers investigated the pharmacodynamic effects of peppermint oil and caraway oil in healthy volunteers, using a unique combination of methods to study the gastrointestinal tract. It's like exploring the vast and intricate digestive system of a camel, revealing the secrets of how these oils affect its function.

Effects on Gastric and Gallbladder Motility

The study revealed that both peppermint oil and caraway oil significantly inhibited gall-bladder emptying, suggesting a relaxing effect on this organ. Peppermint oil was also found to prolong orocaecal transit time, suggesting a slower small intestinal transit. It's like observing a camel's digestive system, where the oils are like subtle regulators, influencing the pace and flow of the journey through the gut.

Dr.Camel's Conclusion

This study provides valuable insights into the effects of peppermint oil and caraway oil on gastrointestinal motility. While further research is needed to fully understand their therapeutic potential, these findings suggest that they may have a role in addressing specific digestive issues. It's like discovering a new oasis in the desert of digestive health, offering potential solutions for a range of gastrointestinal discomforts.

Date :
  1. Date Completed 2003-04-16
  2. Date Revised 2021-12-03
Further Info :

Pubmed ID

12562459

DOI: Digital Object Identifier

10.1046/j.1365-2036.2003.01421.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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