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Relapse of Graves' disease after successful outcome of antithyroid drug therapy: results of a prospective randomized study on the use of levothyroxine.

Author: , DettmannJuergen, HackenbergKlaus, HircheHerbert, HoermannRudolf, MannKlaus, MengWieland, PfeilschifterJohannes, PrehnBrigitte, QuadbeckBeate, ReschkeKirsten, RoggenbuckUlla, SzabolcsIstván

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Levothyroxine therapy did not prevent relapse of hyperthyroidism after successful restoration of euthyroid function by antithyroid drugs. The study demonstrates that posttreatment thyrotropin (TSH) is a main prognostic marker for relapse.
Paper Details　
Original Abstract of the Article :
Antithyroid drugs are effective in restoring euthyroidism in Graves' disease, but many patients experience relapse after withdrawal. Prevention of recurrence would therefore be a desirable goal. In a prospective study, patients with successful outcome of 12 to 15 months antithyroid drug therapy were...See full text at original site
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引用元：
https://doi.org/10.1089/105072502321085225

データ提供：米国国立医学図書館（NLM）

Graves' Disease: A Camel's Journey Through Thyroid Health

Graves' disease, like a desert mirage, can be a perplexing and challenging condition. This study, like a meticulous researcher, investigates the effectiveness of levothyroxine in preventing relapse after successful treatment with antithyroid drugs. The researchers conducted a prospective randomized study, finding that levothyroxine did not significantly prevent relapse of hyperthyroidism in patients with Graves' disease. This underscores the need for alternative strategies to manage Graves' disease and prevent long-term complications. It's like discovering that a shimmering oasis is not as reliable as it first appeared, prompting us to seek new solutions.

The Shifting Sands of Graves' Disease: Understanding Relapse

The study's findings highlight the challenges of preventing relapse in Graves' disease, emphasizing the need for ongoing research and the development of new treatment strategies. It's like navigating a desert landscape where the sand dunes constantly shift, requiring constant adaptation and vigilance.

A Camel's Advice: Staying Hydrated and Seeking the Right Care

If you are diagnosed with Graves' disease, it's essential to work closely with your endocrinologist to develop a comprehensive management plan. This includes discussing treatment options, monitoring your thyroid function, and understanding the potential risks and benefits of various therapies. Remember, staying hydrated and seeking the right care are crucial for navigating the desert of Graves' disease.

Dr. Camel's Conclusion

This study highlights the challenges of managing Graves' disease and preventing relapse. It emphasizes the importance of ongoing research to develop effective and long-term treatment strategies for this complex condition. Like a resilient camel adapting to the desert's changing landscape, we must continue to explore and innovate to improve the lives of those living with Graves' disease.

Date :
  1. Date Completed 2003-07-17
  2. Date Revised 2016-11-24
Further Info :

Pubmed ID

12593726

DOI: Digital Object Identifier

10.1089/105072502321085225

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Languages

English

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