Pain treatment with a COX-2 inhibitor after coronary artery bypass operation: a randomized trial.

Author: BerdatPascal A, CarrelThierry P, CuratoloMichele, EigenmannVerena, ImmerFranz F, Immer-BansiAlexsandra S, TrachselNathalie

Paper Details 
Original Abstract of the Article :
BACKGROUND: Adequate analgesic medication is mandatory after cardiac operations. Cyclooxygenase-2 inhibitors represent a new therapeutic option, acting primarily on the response to inflammation. METHODS: We compared a cyclooxygenase-2 inhibitor (etodolac) with two traditional drugs: a nonselective ...See full text at original site
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引用元:
https://doi.org/10.1016/s0003-4975(02)04311-4

データ提供:米国国立医学図書館(NLM)

Postoperative Pain Relief: A Cool Oasis After Bypass Surgery

Coronary artery bypass surgery is a major operation that requires careful management of postoperative pain. This research compares the effectiveness of different pain medications, including a COX-2 inhibitor (etodolac), a nonselective cyclooxygenase inhibitor (diclofenac), and a weak opioid (tramadol), in managing pain after bypass surgery.

The researchers found that etodolac and diclofenac provided better pain relief with fewer side effects than tramadol. However, they also noted that both etodolac and diclofenac were associated with a temporary increase in creatinine levels, a marker of kidney function. Think of it as navigating a desert with different types of camels - some camels are strong and fast, but they require more care and attention.

Navigating the Postoperative Desert

This research suggests that COX-2 inhibitors and nonselective cyclooxygenase inhibitors could be effective options for managing postoperative pain, but careful monitoring of kidney function is essential.

Pain Management: Finding the Right Oasis

This research emphasizes the importance of individualizing pain management plans, considering the patient's overall health status and potential risks. It's essential to work closely with a healthcare professional to find the most appropriate and effective pain relief strategy.

Dr.Camel's Conclusion

This research provides valuable insights into the evolving landscape of postoperative pain management. It highlights the potential benefits of COX-2 inhibitors and underscores the need for ongoing research to optimize pain relief and minimize potential side effects.

Date :
  1. Date Completed 2003-03-17
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

12607659

DOI: Digital Object Identifier

10.1016/s0003-4975(02)04311-4

Related Literature

SNS
PICO Info
in preparation
Languages

English

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