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Effects of patch or gel estrogen therapies on auditory brainstem response in surgically postmenopausal women: a prospective, randomized study.

Author: AgnelloCarmela, CarusoSalvatore, Di MariLucia, GarozzoAldo, MaiolinoLuigi, SerraAgostino

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Transdermal estrogen therapy (ET) using either patch or gel formulations improved auditory brainstem response in surgically postmenopausal women. The wave latencies and interpeak intervals were lower during ET treatment compared to baseline levels. This suggests that fluctuating estrogen levels may influence neuronal plasticity and neurotransmitter levels, affecting neuronal conduction time within the audiological system.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To study the effects of gonadal steroids on the nongenital audiological target in surgically postmenopausal women treated with patch or gel transdermal estrogen therapy (ET). DESIGN: Prospective randomized study. SETTING: Research Group for Sexology, University of Catania, Italy. PATIE...See full text at original site
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引用元：
https://doi.org/10.1016/s0015-0282(02)04763-5

データ提供：米国国立医学図書館（NLM）

Estrogen's Impact on Hearing: A New Perspective on Hormonal Effects

This research delves into the intriguing relationship between hormones and hearing. The study focuses on the effects of estrogen therapy (ET) on auditory brainstem response (ABR), an important measure of hearing function. The study employs a prospective, randomized design, a gold standard for investigating treatment effects.

Estrogen and Auditory Function: Exploring the Connection

The study reveals that transdermal ET, administered either as a patch or gel, can significantly improve ABR values in surgically postmenopausal women. This finding suggests a potential role for estrogen in maintaining auditory function, even beyond its traditional reproductive roles. It's like discovering a hidden oasis in the desert, revealing an unexpected and crucial connection between hormones and hearing.

Listen Up! The Impact of Estrogen on Hearing

The study's findings could have important implications for understanding the effects of estrogen on hearing and potentially for developing new treatments for hearing loss. This knowledge is like a map leading us to a deeper understanding of the intricate relationship between hormones and auditory function. It encourages us to consider the potential impact of hormones on various aspects of our health, beyond their traditional roles.

Dr. Camel's Conclusion

This research adds a new dimension to our understanding of estrogen's role in the body. By highlighting its impact on auditory function, the study opens a new frontier in the field of hormonal research. It's like discovering a new desert oasis, revealing a hidden connection between hormones and hearing. This discovery could lead to new insights into the causes and treatments of hearing loss, ultimately improving the quality of life for individuals experiencing these challenges.

Date :
  1. Date Completed 2003-04-04
  2. Date Revised 2019-07-07
Further Info :

Pubmed ID

12620439

DOI: Digital Object Identifier

10.1016/s0015-0282(02)04763-5

SNS
PICO Info
in preparation
Languages

English

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