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Effects of treatment with etidronate and alfacalcidol for osteogenesis imperfecta type I: a case report.
Author: IchimuraShoichi, IwamotoJun, MatsuKenjiro, TakedaTsuyoshi, UzawaMitsuyoshi
Original Abstract of the Article :
A case of osteogenesis imperfecta (OI) that was successfully treated with oral etidronate and alfacalcidol is reported. A 36-year-old man with OI type I who had frequently been experiencing fragile fractures in the long bones of the upper and lower extremities presented to our hospital with back pai...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/12665966
データ提供:米国国立医学図書館(NLM)
Osteogenesis Imperfecta: A Case of Successful Treatment with Etidronate and Alfacalcidol
Osteogenesis imperfecta (OI) is a rare genetic disorder characterized by fragile bones, leading to frequent fractures and significant pain. This case report details the successful treatment of a 36-year-old man with OI type I using a combination of etidronate and alfacalcidol. The authors report a significant increase in bone mineral density and a reduction in back pain associated with vertebral fractures following treatment.
Etidronate and Alfacalcidol: A Potential Treatment for OI
The case report suggests that intermittent cyclical treatment with etidronate and alfacalcidol may be a viable therapeutic option for adults with OI type I. The study's findings provide encouraging evidence for the potential benefits of this treatment regimen, highlighting its ability to improve bone mineral density and reduce pain associated with fractures. It's like finding a hidden oasis in a barren desert, offering hope and relief for individuals with OI.
Navigating the Challenges of OI Treatment
This research underscores the importance of exploring novel treatment options for OI. The study's findings provide a promising avenue for further investigation into the use of etidronate and alfacalcidol in the management of OI. It is crucial to conduct larger clinical trials to confirm the efficacy and safety of this treatment regimen in a wider population of OI patients.
Dr.Camel's Conclusion
The case report offers hope for individuals with OI, suggesting that etidronate and alfacalcidol may provide a potential treatment option. Just as a camel can adapt to survive in a challenging desert environment, individuals with OI can find strength and resilience through innovative treatments that improve bone health and reduce pain.
Date :
- Date Completed 2003-08-04
- Date Revised 2013-11-21
Further Info :
Related Literature
English
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