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Individualization of interferon therapy using serum hepatitis B virus DNA to reduce viral relapse in patients with chronic hepatitis B: a randomized controlled trial.

Author: ChungYoung-Hwa, JungSung Ae, LeeGeun Chan, LeeHan Chu, LeeYung Sang, RyuSoo Hyung, ShinJung Woo, SongByung-Cheol, SuhDong Jin, YooKwon

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Hepatitis B often returns after interferon treatment. This study investigated whether customizing the length of interferon treatment based on the amount of virus in the blood could reduce the risk of the virus returning in patients with chronic hepatitis B who responded well to treatment.
Paper Details　
Original Abstract of the Article :
In patients with chronic hepatitis B, viral relapse following interferon (IFN) therapy may be the result of a treatment duration that is too short to prevent hepatitis B virus (HBV) from replicating later. To reduce viral relapse in patients with chronic hepatitis B who responded to IFN, we individu...See full text at original site
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引用元：
https://doi.org/10.1097/01.meg.0000059120.41030.52

データ提供：米国国立医学図書館（NLM）

Individualizing Interferon Therapy for Chronic Hepatitis B

This research explores the field of [hepatitis B] and [viral infection], investigating the potential benefits of individualized interferon therapy for patients with chronic hepatitis B. The researchers conducted a [randomized controlled trial] to evaluate the effectiveness of adjusting the duration of interferon therapy based on serum hepatitis B virus (HBV) DNA levels. The study found that [individualizing interferon therapy based on HBV DNA levels can effectively reduce viral relapse]. This finding underscores the importance of [personalized treatment approaches] in managing chronic hepatitis B.

Tailoring Treatment for Chronic Hepatitis B

The study's results demonstrate the effectiveness of [individualizing interferon therapy] for patients with chronic hepatitis B. The findings suggest that [monitoring HBV DNA levels during treatment can help to determine the optimal duration of therapy].

Navigating the Desert of Viral Infections

Just as a camel navigates the vast and unpredictable desert, our bodies are constantly battling a myriad of viral infections. This research highlights the importance of [adapting treatment strategies] to meet the unique challenges posed by each individual's immune system.

Dr.Camel's Conclusion

This study reminds us that one size does not fit all when it comes to treating chronic hepatitis B. By [individualizing treatment strategies] and monitoring viral load, we can improve the outcomes for patients with chronic hepatitis B.

Date :
  1. Date Completed 2003-07-14
  2. Date Revised 2014-11-20
Further Info :

Pubmed ID

12702905

DOI: Digital Object Identifier

10.1097/01.meg.0000059120.41030.52

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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