Induction interferon and ribavirin for re-treatment of chronic hepatitis C patients unresponsive to interferon alone.

Author: , BateyR, BhathalP, BowdenS, De SolomR, MarinosG, McDonaldJ, MollisonL, PiankoS, ReedW, SievertW, WarnerS

Paper Details 
Original Abstract of the Article :
BACKGROUND: The optimal treatment for hepatitis C patients unresponsive to interferon is unclear. High-dose induction interferon may enhance early viral clearance, whilst ribavirin reduces relapse; in combination, they may improve sustained virological response rates. AIM: To compare the efficacy a...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1046/j.1365-2036.2003.01544.x

データ提供:米国国立医学図書館(NLM)

Combating Hepatitis C: A Multi-Pronged Approach

Hepatitis C is a serious liver disease that can lead to chronic infection and liver damage. This study explores the effectiveness of a combination therapy for patients who have not responded to interferon alone, a standard treatment for hepatitis C. The researchers investigated the use of high-dose induction interferon, a more aggressive approach, combined with ribavirin, an antiviral drug, to improve treatment outcomes. The study involved 218 patients who had not achieved a sustained virological response to interferon alone. They were randomly assigned to receive either the high-dose induction interferon with ribavirin or the same interferon regimen with a placebo. The results were encouraging. The sustained virological response rate was significantly higher in the group receiving the combination therapy compared to the placebo group. This suggests that high-dose induction interferon combined with ribavirin may offer a more effective treatment option for patients who have not responded to interferon alone.

A Journey Through the Desert of Hepatitis C

The study findings offer a ray of hope for patients struggling with hepatitis C. The combination therapy's improved efficacy suggests that a multi-pronged approach may be more effective in battling this challenging disease.

Navigating the Landscape of Hepatitis C

The research emphasizes the importance of personalized treatment strategies for hepatitis C. The findings suggest that high-dose induction interferon combined with ribavirin may be a viable option for patients who have not responded to interferon alone. However, it's crucial to consult with a healthcare professional to determine the most appropriate treatment plan for your individual needs.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of combination therapy for hepatitis C. The use of high-dose induction interferon combined with ribavirin shows promise for patients who have not responded to interferon alone. This research contributes to the ongoing effort to develop more effective and personalized treatment strategies for hepatitis C, offering hope for those navigating the challenges of this disease.

Date :
  1. Date Completed 2003-06-23
  2. Date Revised 2019-09-01
Further Info :

Pubmed ID

12752357

DOI: Digital Object Identifier

10.1046/j.1365-2036.2003.01544.x

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.