The efficacy and tolerability of sildenafil in patients with moderate-to-severe pulmonary hypertension.

Author: BharaniAnil, LuniaBasant, MathewVivek, SahuAshutosh

Paper Details 
Original Abstract of the Article :
Pulmonary arterial hypertension is a life-threatening disease for which continuous intravenous infusion of prostacyclin has proved effective. However, it carries the risk of serious complications arising from the complex delivery system. Prostacyclin analogs, endothelin antagonists, and the phosphod...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/12760589

データ提供:米国国立医学図書館(NLM)

Sildenafil: A Beacon of Hope in the Treatment of Pulmonary Hypertension

The [pulmonary circulation] is a vital component of our circulatory system, and disruptions in its function can lead to serious and life-threatening conditions such as [pulmonary hypertension]. This study explores the potential of [sildenafil], a [phosphodiesterase-5 inhibitor], as a treatment option for patients with [pulmonary hypertension]. The authors investigated the [efficacy] and [tolerability] of [sildenafil] in patients with [moderate-to-severe pulmonary hypertension], who were poorly controlled on conventional treatments.

Sildenafil: A New Frontier in Pulmonary Hypertension Treatment

The study suggests that [sildenafil] may hold promise as a [novel therapy] for patients with [pulmonary hypertension]. The researchers observed [positive effects] on [hemodynamics] and [exercise capacity] in patients treated with [sildenafil]. The study also highlighted the [tolerability] of [sildenafil], with [minimal adverse effects] reported. These findings offer hope for a new generation of treatments for this challenging condition.

Navigating the High Peaks of Pulmonary Hypertension: Sildenafil as a Guide

This research underscores the importance of developing [effective treatments] for [pulmonary hypertension]. The findings suggest that [sildenafil] may play a significant role in [improving patient outcomes] and [enhancing quality of life] for those suffering from this condition. The study provides valuable insights into the potential of [phosphodiesterase-5 inhibitors] as a new avenue for [pulmonary hypertension] management.

Dr.Camel's Conclusion

The challenges posed by [pulmonary hypertension] can feel as daunting as traversing a mountain range. This study offers a beacon of hope, suggesting that [sildenafil] may provide a valuable path toward improved treatment and a better quality of life for patients grappling with this condition.

Date :
  1. Date Completed 2003-09-03
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

12760589

DOI: Digital Object Identifier

12760589

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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