Paper Details

  1. Home
  2. Paper Details

Azelastine nasal spray: a review of pharmacology and clinical efficacy in allergic and nonallergic rhinitis.

Author: LiebermanPhillip L, SettipaneRussell A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article reviews the pharmacological profile, clinical efficacy, and safety of azelastine nasal spray for the treatment of seasonal allergic rhinitis and nonallergic vasomotor rhinitis.
Paper Details　
Original Abstract of the Article :
Azelastine hydrochloride is a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflammatory activity. Azelastine has established antiallergic and anti-inflammatory effects that are unrelated to H1-receptor antagonism, including inhibitory effects on th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/12776442

データ提供：米国国立医学図書館（NLM）

Azelastine: A Multifaceted Approach to Rhinitis Relief

This article reviews the pharmacological profile and clinical efficacy of azelastine hydrochloride, a pharmacologically distinct H1-receptor antagonist with a broad spectrum of antiallergic and anti-inflammatory activity. Azelastine has established antiallergic and anti-inflammatory effects that go beyond H1-receptor antagonism. The article highlights azelastine's ability to inhibit the synthesis of leukotrienes, kinins, and cytokines, as well as its effects on the generation of superoxide free radicals and the expression of intercellular adhesion molecule 1. The article concludes that azelastine nasal spray is an effective treatment for both seasonal allergic rhinitis and nonallergic vasomotor rhinitis.

Azelastine: A Comprehensive Solution for Rhinitis

This article provides a comprehensive overview of the pharmacological and clinical properties of azelastine, highlighting its effectiveness in treating both allergic and nonallergic rhinitis. The authors emphasize the multi-faceted nature of azelastine's anti-inflammatory activity, suggesting that it offers a potentially superior approach to traditional antihistamines.

Azelastine: A Breath of Fresh Air for Rhinitis Sufferers

Like a cool breeze in the desert, azelastine offers relief from the discomfort of rhinitis. This review highlights the effectiveness of azelastine nasal spray in treating both allergic and nonallergic forms of rhinitis, providing a promising treatment option for those suffering from this common condition.

Dr. Camel's Conclusion

This insightful review provides a comprehensive overview of the pharmacological properties and clinical efficacy of azelastine nasal spray. The authors emphasize the multifaceted nature of azelastine's anti-inflammatory activity and its effectiveness in treating both allergic and nonallergic rhinitis. This information will be valuable for clinicians and patients alike as they seek effective treatment options for rhinitis.
Date :
  1. Date Completed 2003-09-16
  2. Date Revised 2016-10-20
Further Info :

Pubmed ID

12776442

DOI: Digital Object Identifier

12776442

Related Literature

Article Analysis
・Effects of azelastine nasal spray
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.