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Efficacy and safety of azelaic acid (15%) gel as a new treatment for papulopustular rosacea: results from two vehicle-controlled, randomized phase III studies.

Author: GraupeKlaus, ThiboutotDiane, Thieroff-EkerdtRuth

Clinical Trial, Phase IIIA Phase III trial is a trial that further rigorously verifies the efficacy and safety of a new drug or treatment, whose efficacy and safety have been confirmed in a Phase II trial, in a large number of patients, and evaluates whether it is superior to existing treatments.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

15% azelaic acid (AzA) gel was more effective than vehicle in treating moderate, papulopustular rosacea. AzA gel resulted in significantly higher reductions in inflammatory lesion count, improvement in erythema, and therapeutic success compared to vehicle. AzA gel was well tolerated and safe, with no serious treatment-related adverse events reported.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Rosacea is a common, chronic dermatosis for which safe and effective new treatment options are needed. OBJECTIVE: The objective of these studies was to evaluate the efficacy, tolerability, and safety of a new formulation of 15% azelaic acid (15%) gel (AzA gel), for the topical treatment...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12789172

データ提供：米国国立医学図書館（NLM）

Azelaic Acid Gel: A New Oasis in the Desert of Rosacea Treatment

Rosacea, a common chronic skin condition, can be a frustrating and debilitating experience, like a persistent sandstorm in the desert of the skin. This study, a journey into the world of rosacea treatment, investigated the efficacy and safety of a new formulation of 15% azelaic acid (AzA) gel for the treatment of moderate, papulopustular rosacea.

Azelaic Acid Gel: A Beacon of Hope in the Desert of Rosacea

This study, a comprehensive investigation into the efficacy of AzA gel, demonstrates that AzA gel is an efficacious, safe, and well-tolerated topical treatment for moderate, papulopustular rosacea. The results, like a refreshing oasis in the desert of rosacea, reveal that AzA gel effectively reduces inflammatory lesions and improves erythema, offering a valuable new option for patients struggling with this challenging skin condition.

Navigating the Desert of Rosacea: A New Era of Treatment

The study highlights the potential of AzA gel to effectively treat moderate, papulopustular rosacea. This research, like a skilled camel navigating a treacherous terrain, paves the way for a new era of rosacea treatment, offering patients more effective and well-tolerated therapies to combat this challenging skin condition.

Dr. Camel's Conclusion

This research provides valuable insights into the treatment of rosacea. AzA gel, like a new oasis in the desert, offers a promising new option for patients struggling with this challenging skin condition. The study underscores the importance of seeking effective treatment options to improve the quality of life for patients facing the challenges of rosacea.
Date :
  1. Date Completed 2003-07-14
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

12789172

DOI: Digital Object Identifier

S0190-9622(03)00405-5

Related Literature

Article Analysis
・Effective treatment of rosacea
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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