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[Combined effects of toremifene and paclitaxel on human breast cancer cell lines].
Author: KuroiwaShunsuke, MaruyamaSakiko, NishikawaKiyohiro, SaimotoAtsuya
Original Abstract of the Article :
Effects of toremifene (TOR) in combination with paclitaxel (TXL) on various human breast cancer cell lines were evaluated. TOR and TXL exhibited additive effects on estrogen receptor (ER)-positive cancer cell lines, MCF-7 and T-47D, and a sub-additive effect on a tamoxifen (TAM)-resistant line, T-47...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/12795099
データ提供:米国国立医学図書館(NLM)
A Powerful Duo: Combining Toremifene and Paclitaxel for Breast Cancer Treatment
This study investigates the potential of combining toremifene, a selective estrogen receptor modulator, and paclitaxel, a chemotherapy drug, for treating breast cancer. The researchers evaluated the effects of this combination therapy on various human breast cancer cell lines, examining both their effectiveness and their potential side effects. It's like blending two potent desert herbs, creating a powerful elixir that can potentially combat disease.
A Promising Combination for Breast Cancer Treatment
The study found that the combination of toremifene and paclitaxel exhibited additive or synergistic effects on various breast cancer cell lines, including both estrogen receptor (ER)-positive and ER-negative lines. This combination therapy was also effective in overcoming drug resistance, suggesting that it could be a promising treatment option for patients with resistant tumors.
Finding New Ways to Fight Breast Cancer
This study highlights the potential of combining different therapies to enhance the treatment of breast cancer. By understanding the synergistic effects of different drugs, we can develop more effective and targeted treatments that improve patient outcomes. It's like a desert caravan, where each member contributes its unique strengths to ensure the success of the journey.
Dr.Camel's Conclusion
This research, like a camel caravan seeking the most valuable oasis in the desert, reveals the potential of combining toremifene and paclitaxel for breast cancer treatment. By understanding the synergistic effects of different therapies, we can potentially develop new and more effective treatments that improve patient outcomes. Just as a camel adapts to the challenges of the desert, we must find ways to adapt our treatment strategies to combat the complexities of breast cancer.
Date :
- Date Completed 2003-06-17
- Date Revised 2015-11-19
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