Chemotherapy alone versus endocrine therapy alone for metastatic breast cancer.

Author: GhersiD, HornbuckleJ, WilckenN

Paper Details 
Original Abstract of the Article :
BACKGROUND: Both chemotherapy and endocrine therapy can be used as treatments for metastatic breast cancer. OBJECTIVES: To review the evidence and determine whether chemotherapy or endocrine therapy has the most beneficial effect on treatment outcomes (survival, response rate, toxicity and quality ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094405/

データ提供:米国国立医学図書館(NLM)

Chemotherapy vs. Endocrine Therapy: Navigating the Sands of Metastatic Breast Cancer

Metastatic breast cancer, like a relentless desert wind, poses a formidable challenge for patients and healthcare professionals. This study, like a careful camel caravan traversing a vast and unforgiving landscape, compares two commonly used treatment options: chemotherapy and endocrine therapy. The researchers, like skilled desert navigators, conducted a systematic review of randomized trials, meticulously analyzing data from hundreds of women with metastatic breast cancer. The findings, like a hidden oasis, revealed that there was no significant difference in overall survival between chemotherapy and endocrine therapy alone. However, chemotherapy was associated with a higher response rate, indicating that it might be more effective in shrinking tumors. However, the study also highlighted the greater toxicity associated with chemotherapy, with side effects such as nausea, vomiting, and hair loss. The study concluded that for women with metastatic breast cancer and hormone receptor-positive tumors, endocrine therapy should be considered as the initial treatment option, unless the disease is rapidly progressing.

Finding the Right Path: A Personalized Approach to Breast Cancer Treatment

The study's findings underscore the importance of personalized treatment plans in metastatic breast cancer. While chemotherapy might offer a quicker response, the potential for greater toxicity should be carefully considered. The decision of which treatment path to take is a complex one, requiring careful consultation with a healthcare professional.

Navigating the Desert of Breast Cancer: A Guide for Patients and Caregivers

Living with metastatic breast cancer, like traversing a challenging desert, requires resilience and a strong support network. This study provides valuable insights into the treatment options available, emphasizing the importance of personalized care and informed decision-making.

Dr.Camel's Conclusion

This study, like a caravan navigating the shifting sands of metastatic breast cancer, highlights the importance of personalized treatment approaches. The decision of whether to choose chemotherapy or endocrine therapy is a complex one, requiring a thorough understanding of the risks and benefits associated with each option.

Date :
  1. Date Completed 2003-07-28
  2. Date Revised 2021-05-14
Further Info :

Pubmed ID

12804433

DOI: Digital Object Identifier

PMC8094405

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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