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Interferon alpha therapy in patients with chronic type C hepatitis: changes of serum ALT, anti-HCV & HCV-RNA.

Author: ChoH J, DongS H, HanJ H, KimH Y, LeeM S, ParkC K, PolitoA, QuanS, YooJ Y

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

After the discovery of type C hepatitis virus, recombinant interferon alpha therapy emerged as a common treatment. A study of 10 patients with chronic type C hepatitis treated with interferon alpha for 6 months showed improvements in serum aminotransferase levels, antibody to hepatitis C virus, and HCV ribonucleic acid.
Paper Details　
Original Abstract of the Article :
After the discovery of type C hepatitis virus, the studies on this virus are extensively progressing. The treatment of this viral infection is also widely progressing. Among many agents, recombinant interferon alpha therapy is generally accepted as an effective single agent. To evaluate the efficacy...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.3904/kjim.1992.7.1.13

データ提供：米国国立医学図書館（NLM）

Interferon Alpha Therapy: A Promising Approach to Chronic Hepatitis C

The field of virology is constantly seeking effective treatments for viral infections. This research investigates the use of interferon alpha therapy in patients with chronic hepatitis C, a debilitating viral infection of the liver. The study examines the effectiveness of interferon alpha therapy by evaluating changes in serum aminotransferase (ALT), antibody to hepatitis C virus (anti-HCV), and HCV ribonucleic acid (HCV-RNA) levels in treated patients.

Interferon Alpha: A Potential Weapon Against Hepatitis C

The study found that interferon alpha therapy was effective in treating chronic hepatitis C, leading to significant improvements in ALT, anti-HCV, and HCV-RNA levels. This demonstrates the potential of interferon alpha as a single-agent treatment for chronic hepatitis C, offering hope for patients battling this debilitating infection. The study's findings provide valuable information for clinicians treating patients with hepatitis C.

From Research to Treatment: Implications for Patient Care

This research provides valuable insight into the treatment of chronic hepatitis C. The study's findings support the use of interferon alpha therapy as a single-agent treatment for this condition. This information can help clinicians make informed treatment decisions and provide effective care for patients with chronic hepatitis C.

Dr. Camel's Conclusion

Imagine a shimmering oasis in the heart of a sun-baked desert, offering relief from the relentless heat. Interferon alpha therapy, in this research, is like that oasis, providing hope for individuals battling chronic hepatitis C. This research highlights the potential of interferon alpha therapy as a powerful weapon against this debilitating infection. Just as a traveler in the desert seeks out a life-giving oasis, patients with hepatitis C are searching for effective treatments to regain their health and well-being. This research offers a glimmer of hope on the horizon, a testament to the power of medical science to combat even the most challenging diseases.

Date :
  1. Date Completed 1993-02-11
  2. Date Revised 2019-06-06
Further Info :

Pubmed ID

1282364

DOI: Digital Object Identifier

10.3904/kjim.1992.7.1.13

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・Effective treatment of hepatitis c
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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