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Assessment of adapalene gel for the treatment of actinic keratoses and lentigines: a randomized trial.

Author: GoldfarbMichael T, GriffithsChristopher E M, HamiltonTed A, KangSewon, MetzRussell D, VoorheesJohn J, WeissJonathan S

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Adapalene gel 0.1% and 0.3% were well tolerated and improved actinic keratoses, solar lentigines, and other features of photodamaged skin.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Adapalene is a synthetic retinoid with an established clinical efficacy against acne and good local tolerability. Its effectiveness in the treatment of photodamaged skin has not been studied. OBJECTIVE: We sought to determine the safety and efficacy of adapalene gel in the treatment of ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12833014

データ提供：米国国立医学図書館（NLM）

Adapalene Gel: A Potential Oasis in the Desert of Photodamaged Skin

The landscape of [dermatology] is marked by the quest for effective treatments for various skin conditions. This study explores the potential of adapalene gel, a synthetic retinoid, for treating actinic keratoses and solar lentigines, both common manifestations of photodamaged skin. It's like finding a refreshing oasis in the desert of sun-damaged skin, offering hope for a more effective treatment. The study [research method] to assess the safety and efficacy of adapalene gel in treating actinic keratoses and solar lentigines.

A Tale of Two Concentrations: Adapalene's Effectiveness

The study's findings suggest that adapalene gel, at both 0.1% and 0.3% concentrations, [quantify the improvement] in both actinic keratoses and solar lentigines compared to a vehicle control. This highlights the potential for adapalene gel to effectively address these common skin conditions. It's like discovering two different springs in the desert, both offering refreshing respite for thirsty travelers.

Navigating the Landscape of Photodamaged Skin: Adapalene's Potential

This research highlights the promising role of adapalene gel in treating photodamaged skin. It suggests that adapalene gel can be a valuable tool in the dermatologist's arsenal, offering a potential oasis of relief for those struggling with actinic keratoses and solar lentigines. Like a seasoned desert traveler, dermatologists must continue to explore new avenues for treating these common conditions.

Dr.Camel's Conclusion

This study sheds light on the potential of adapalene gel as a valuable treatment for photodamaged skin. It demonstrates its efficacy in reducing actinic keratoses and solar lentigines, offering a refreshing oasis of relief for those seeking to restore their skin's health. It's a reminder that we must continue to explore new horizons in dermatological research, seeking innovative solutions to the challenges we face in the vast desert of skin conditions.

Date :
  1. Date Completed 2003-07-31
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

12833014

DOI: Digital Object Identifier

S0190962203008077

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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