Inflammation modifies the effects of a reduced-fat low-cholesterol diet on lipids: results from the DASH-sodium trial.

Author: AppelLawrence J, CharlestonJeanne, ErlingerThomas P, MillerEdgar R

Paper Details 
Original Abstract of the Article :
BACKGROUND: Inflammatory mediators regulate key aspects of lipid metabolism. We hypothesized that inflammation could diminish the cholesterol-lowering effect of a reduced-fat/low-cholesterol diet. METHODS AND RESULTS: After a 2-week run-in period on a control diet (37% total fat, 16% saturated fat)...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://pubmed.ncbi.nlm.nih.gov/12847067

データ提供:米国国立医学図書館(NLM)

Inflammation: A Hidden Enemy in Cholesterol Reduction

The desert of cardiovascular disease is a vast and complex landscape, where inflammation plays a significant role. While dietary changes are often recommended to lower cholesterol levels, inflammation can hinder their effectiveness. Imagine cholesterol as a thick layer of sand, hindering the flow of blood through the arteries. A reduced-fat diet acts like a wind that blows away some of the sand, but inflammation, like a desert storm, can bring it back. Understanding the interplay between inflammation and cholesterol is crucial for effectively managing cardiovascular disease.

Inflammation Dampens Cholesterol Reduction

This study shows that inflammation, measured by C-reactive protein (CRP), can significantly impact the effectiveness of a reduced-fat diet for lowering cholesterol levels. Individuals with higher levels of inflammation had a less pronounced reduction in total and LDL cholesterol, while their triglyceride levels increased. It's like the desert storm eroding the progress made by the wind, keeping the sand dunes high.

Managing Inflammation for Optimal Heart Health

Maintaining a healthy lifestyle, including a balanced diet and regular exercise, can help to reduce inflammation and improve cholesterol levels. Understanding the role of inflammation is essential for managing cardiovascular disease effectively. It's like navigating the desert strategically, avoiding the storms and seeking out the oases of good health.

Dr.Camel's Conclusion

Inflammation can be a hidden enemy in the fight against cardiovascular disease. Understanding the impact of inflammation on cholesterol levels is crucial for effective management. By adopting a healthy lifestyle, we can navigate the desert of cardiovascular disease and maintain a healthy heart.

Date :
  1. Date Completed 2003-08-05
  2. Date Revised 2022-02-27
Further Info :

Pubmed ID

12847067

DOI: Digital Object Identifier

01.CIR.0000080288.30567.86

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.