A clinical trial of oxantel and pyrantel against intestinal nematodes infections.

Author: ChoiWon Young, ChungChang Seng, KimWun Kyu, LeeOk Ran, LeeWon Koo, OughByong Ok

Paper Details 
Original Abstract of the Article :
This study was conducted to determine the effect of oxantel/pyrantel tablets, oxantel suspension, pyrantel dry syrup and pyrantel tablets against T. trichiurus and A. lumbricoides infections. Twenty-four cases of mixed infections of T. trichiurus and A. lumbricoides were treated with oxantel/pyrante...See full text at original site
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引用元:
https://doi.org/10.3347/kjp.1979.17.1.60

データ提供:米国国立医学図書館(NLM)

A Study on the Effectiveness of Oxantel and Pyrantel Against Intestinal Nematodes

This research delves into the realm of [parasitology], a field that seeks to unravel the intricate relationships between parasites and their hosts. This particular study employed a [clinical trial] design to investigate the efficacy of oxantel/pyrantel tablets, oxantel suspension, pyrantel dry syrup, and pyrantel tablets against [T. trichiurus and A. lumbricoides] infections. The researchers meticulously analyzed [egg negative conversion rate and egg reduction rate] before and after drug administration, demonstrating [the varying degrees of effectiveness across different drug formulations and parasite species]. This study's key findings highlight [the potential of oxantel and pyrantel as effective treatments for intestinal nematodes, with specific considerations for dosage and parasite type].

Effectiveness of Oxantel and Pyrantel Against Intestinal Nematodes

The results of this study indicate [a high degree of effectiveness] of oxantel and pyrantel in treating [T. trichiurus and A. lumbricoides] infections. For instance, [oxantel/pyrantel tablets at a single dose of 20 mg/kg body weight] achieved a [75.0%] egg negative conversion rate and [97.8%] egg reduction rate in [T. trichiurus] infection. Moreover, [oxantel suspension at a single dose of 15 mg/kg body weight] yielded an [85.7%] egg negative conversion rate and [93.0%] egg reduction rate in [single infection of T. trichiurus]. These findings are truly remarkable, providing much-needed information for [effective treatment strategies] in [parasitology] research.

Implications for Intestinal Nematode Infections

Understanding the [efficacy of oxantel and pyrantel] against intestinal nematodes is a crucial step in [public health] efforts. This research provides valuable insight into [the potential of these drugs as effective treatments] for [T. trichiurus and A. lumbricoides] infections. This knowledge can be directly applied in [clinical practice], contributing to [the development of targeted and efficient treatment protocols] for these widespread parasitic diseases. It's important to note that [the effectiveness can vary depending on the specific parasite species and the dosage administered]. Therefore, a personalized approach, tailored to the individual patient's needs, is essential for [optimizing treatment outcomes] and achieving [successful eradication of intestinal nematodes].

Dr.Camel's Conclusion

This research is a beacon of hope in the vast desert of [parasitology] research, shedding light on [the efficacy of oxantel and pyrantel against intestinal nematodes]. It's like discovering a hidden oasis in the desert, providing much-needed relief from [the burden of parasitic infections]. The researchers' dedication to [scientific inquiry] has yielded valuable insights that can be used to improve [public health] and alleviate [the suffering caused by parasitic diseases] in [communities worldwide].
Date :
  1. Date Completed n.d.
  2. Date Revised 2019-11-20
Further Info :

Pubmed ID

12902761

DOI: Digital Object Identifier

10.3347/kjp.1979.17.1.60

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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