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A role for the periaqueductal grey in opioidergic inhibition of maternal behaviour.

Author: CanterasNewton S, FelicioLuciano F, Miranda-PaivaCláudia M, Ribeiro-BarbosaErika R

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

The periaqueductal gray (PAG) is a brain region involved in the opioidergic blockade of maternal behavior in rats. Morphine's inhibitory effect on maternal responsiveness was blocked by naloxone injection into the rostral PAG.
Paper Details　
Original Abstract of the Article :
Opiates are known to be involved in the regulation of various events surrounding parturition and lactation, such as maternal behaviour in rats. The onset of this behaviour has been closely linked to opiate action in the medial pre-optic area, where administration of morphine disrupts maternal behavi...See full text at original site
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引用元：
https://doi.org/10.1046/j.1460-9568.2003.02794.x

データ提供：米国国立医学図書館（NLM）

The periaqueductal grey and maternal behaviour: A journey into the depths of the maternal brain

The world of maternal behaviour is a fascinating and complex one, like a hidden oasis in the vast desert of neuroscience. This study delves into the role of the periaqueductal grey (PAG) in regulating maternal behaviour, exploring how this region of the brain might act as a gatekeeper for this essential instinct.

Researchers used a combination of pharmacological manipulations and Fos protein immunohistochemical detection to investigate the PAG’s involvement in opioidergic inhibition of maternal behaviour. They discovered that the rostral lateral PAG plays a crucial role in blocking maternal behaviour in response to morphine, a known opiate. It’s like finding a hidden spring that regulates the flow of water in the desert, controlling the lushness of the oasis.

The PAG’s role in maternal behaviour

The study’s findings suggest that the rostral lateral PAG may be a key player in regulating maternal behaviour, acting like a switch that can be turned on or off by opiate drugs. It’s a fascinating glimpse into the complexity of the brain and its intricate role in shaping our behaviours.

Implications for understanding maternal behaviour and the effects of drugs

This research offers valuable insights into the neurological mechanisms underlying maternal behaviour and the potential effects of drugs on this essential instinct. It’s a reminder that even in the depths of the brain, there are intricate pathways and connections that shape our actions and behaviours.

Dr.Camel's Conclusion

This study sheds light on the intricate relationship between the periaqueductal grey and maternal behaviour. It’s like discovering a hidden oasis in the desert of the brain, a region that holds the keys to understanding this essential instinct. This research offers valuable insights into the complex interplay between the brain, behaviour, and the effects of drugs.

Date :
  1. Date Completed 2003-10-03
  2. Date Revised 2019-08-15
Further Info :

Pubmed ID

12911762

DOI: Digital Object Identifier

10.1046/j.1460-9568.2003.02794.x

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Languages

English

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