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Antiproteinuric effects of enalapril and losartan: a pilot study.

Author: HurleyRobert Morrison, MacphersonCatherine Fiona, MatsellDouglas George, WhiteColin Thomas

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Enalapril and losartan were both effective in reducing proteinuria in children with proteinuria and underlying renal injury.
Paper Details　
Original Abstract of the Article :
In this randomized double-blind crossover trial we compared the antiproteinuric effects of enalapril and losartan in six children with proteinuria and underlying renal injury. The primary endpoint was reduction in proteinuria during therapy. The study had two 8-week on-drug arms, with a 4-week washo...See full text at original site
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引用元：
https://doi.org/10.1007/s00467-003-1190-5

データ提供：米国国立医学図書館（NLM）

Enalapril and Losartan: A Tale of Two Drugs in the Desert of Proteinuria

The desert of proteinuria, like a vast and unforgiving landscape, can lead to serious health complications. This research, like a scientific expedition, explores the effectiveness of two drugs, enalapril and losartan, in reducing proteinuria in children with underlying renal injury. The researchers conducted a randomized, double-blind crossover trial to compare the antiproteinuric effects of these two medications, offering valuable insights for clinicians seeking the best treatment options for their young patients.

Enalapril and Losartan: Two Paths Through the Desert of Proteinuria

The study found that both enalapril and losartan effectively reduced proteinuria in children, suggesting that both medications are viable options for managing this condition. While both drugs demonstrated effectiveness, enalapril appeared to have a slightly greater reduction in proteinuria. This finding is like discovering two pathways through the desert, each offering a chance to reach the oasis of health.

Navigating the Desert of Proteinuria: A Guide for Parents

This research provides valuable insights into the treatment of proteinuria in children with renal injury. Both enalapril and losartan offer effective solutions for managing this condition, offering a chance to improve renal health. This research is like a map in the desert, guiding us towards better treatment options for young patients with this challenging condition.

Dr. Camel's Conclusion

This research ventures into the desert of proteinuria, exploring the effectiveness of two medications in managing this condition. The findings highlight the potential of both enalapril and losartan in reducing proteinuria, offering hope for children with renal injury. This study is like a camel caravan, carrying the promise of improved health and a smoother journey through the desert of proteinuria.

Date :
  1. Date Completed 2004-06-09
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

12920631

DOI: Digital Object Identifier

10.1007/s00467-003-1190-5

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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