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[Anaphylaxia induced by etoposide--a case report].

Author: AidaKeiko, AyabeTakuya, FuruyaUshio, HoriYuko, MachidaRyouta, MoriHiroyuki, MuraseTakayuki, OheEiichi, ShinozukaNorio, TaguchiAkinori, TakeshitaShigeki

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

A 32-year-old woman experienced an anaphylactic reaction to etoposide, a chemotherapy drug used for choriocarcinoma. The reaction was successfully managed by administering hydroxyzine hydrochloride and modifying the etoposide regimen. This case highlights the importance of being aware of potential anaphylactic reactions to chemotherapeutic agents.
Paper Details　
Original Abstract of the Article :
A 32-year-old woman, gravida 4, para 2, visited Teikyo University Hospital with complaints of abnormal uterine bleeding and lower abdominal pain. Urine hCG level was 1,024 x 10(3) IU/l. MRI examination showed a vascular, rich solid mass 10 cm in diameter at the posterior region of the uterus. Under ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/12938279

データ提供：米国国立医学図書館（NLM）

A Sandstorm in the Desert of Chemotherapy

The desert of cancer treatment is often fraught with challenges, and unexpected sandstorms can arise. This study, like a research expedition encountering a sudden storm, highlights the potential for anaphylaxis, a severe allergic reaction, to occur during chemotherapy. The researchers, much like skilled navigators, encountered a case of anaphylaxis in a patient receiving etoposide, a key chemotherapeutic agent used to treat choriocarcinoma, a type of cancer. The study emphasizes the importance of recognizing the potential for anaphylaxis and adapting treatment regimens to mitigate risk. This involves careful monitoring of the patient during chemotherapy and prompt intervention in case of allergic reactions. The study also highlights the need for research into alternative chemotherapeutic agents or strategies to reduce the risk of anaphylaxis in vulnerable patients.

Weathering the Storm: Managing Anaphylaxis

The study emphasizes the importance of being prepared for unexpected storms, much like a caravan traveling through the desert. The researchers modified the patient's chemotherapy regimen by pre-treating her with hydrocortisone and promethazine, diluting the etoposide concentration, and reducing the drug administration rate. This helped prevent further episodes of anaphylaxis, allowing the patient to continue her chemotherapy safely.

Navigating the Desert of Chemotherapy: A Vigilant Journey

The study serves as a reminder that navigating the desert of chemotherapy requires vigilance and adaptability. The researchers, much like skilled desert navigators, learned to anticipate and manage potential challenges, ensuring the safety and well-being of their patients.

Dr. Camel's Conclusion

This study serves as a crucial reminder that even in the vast desert of medical advancements, unexpected storms can arise. The researchers effectively navigated this storm by modifying the treatment regimen and employing a vigilant approach.

Date :
  1. Date Completed 2003-09-16
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

12938279

DOI: Digital Object Identifier

12938279

SNS
PICO Info
in preparation
Languages

Japanese

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