Effects of vinblastine on healing in microvascular anastomosis.

Author: GulMustafa, KabukcuogluFevziye, KarsidagSemra Hacikerim, KuranIsmail, TatlidedeSoner, TosunUgur

Paper Details 
Original Abstract of the Article :
Reconstructive microsurgical procedures are getting more common in cancer patients. Adjuvant therapies, such as chemotherapy, radiotherapy, and immune therapy, are usually combined with surgical approaches to improve outcomes. This study was designed to investigate the effects of preoperative chemot...See full text at original site
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引用元:
https://doi.org/10.1002/micr.10144

データ提供:米国国立医学図書館(NLM)

Vinblastine and Microsurgery: A Balancing Act

This study in the field of microsurgery investigates the effects of the chemotherapy drug vinblastine on healing in microvascular anastomosis. The authors conducted an experimental study using rats to determine whether preoperative chemotherapy with vinblastine could impact the success of microsurgical procedures.

Healing Under the Microscope

The study found that the administration of vinblastine, while causing a temporary period of neutropenia, did not significantly affect the healing process in microvascular anastomosis. The patency rates and histopathological findings were comparable between the experimental and control groups, suggesting that vinblastine did not negatively impact healing in this setting.

Balancing Cancer Treatment and Microsurgery

This study provides valuable insights into the potential compatibility of chemotherapy with microsurgical procedures. It suggests that vinblastine, a common chemotherapy drug, can be administered without compromising the healing process in microvascular anastomosis. This research offers hope for patients requiring both chemotherapy and microsurgical interventions, suggesting that these treatments can be combined safely and effectively.

Dr.Camel's Conclusion

This research explores the impact of chemotherapy on the delicate world of microsurgery. The findings suggest that vinblastine, a commonly used chemotherapy drug, does not significantly hinder the healing process in microvascular anastomosis. This study provides valuable information for clinicians managing patients who require both chemotherapy and microsurgical procedures, suggesting that these treatments can be safely combined.

Date :
  1. Date Completed 2004-01-08
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

12942526

DOI: Digital Object Identifier

10.1002/micr.10144

Related Literature

SNS
PICO Info
in preparation
Languages

English

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