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Infliximab in patients who have spondyloarthropathy: clinical efficacy, safety, and biological immunomodulation.

Author: BaetenDominique, De KeyserFilip, KruithofElli, MielantsHerman, Van den BoschFilip, VeysEric M

Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

TNF-alpha blockade is now a successful treatment for ankylosing spondylitis (AS) and other types of spondyloarthritis (SpA), establishing a new indication for this type of anticytokine therapy.
Paper Details　
Original Abstract of the Article :
A major breakthrough has been achieved in the treatment of patients who have AS and other types of SpA. The identification of the expression and role of TNF-alpha in patients who have these diseases and the recognition of their relation with gut inflammation (where infliximab therapy has proven effi...See full text at original site
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引用元：
https://doi.org/10.1016/s0889-857x(03)00052-8

データ提供：米国国立医学図書館（NLM）

A New Era of Treatment for Spondyloarthropathy: Infliximab's Promising Role

Spondyloarthropathy, a group of inflammatory diseases, can be a challenging condition, impacting joints and causing significant pain and discomfort. This study explores the revolutionary potential of infliximab, a biologic drug that targets TNF-alpha, a key player in the inflammatory process. Researchers aimed to assess the efficacy, safety, and biological immunomodulatory effects of infliximab in patients with spondyloarthropathy, hoping to unlock a new era of treatment for this debilitating condition. Their findings revealed that infliximab demonstrated significant clinical efficacy, leading to improvements in both axial and peripheral disease. This groundbreaking discovery opens new avenues for treatment, offering hope to those battling the challenges of spondyloarthropathy.

A Beacon of Hope: Infliximab's Impact on Spondyloarthropathy

The study's findings provide a much-needed beacon of hope for patients with spondyloarthropathy, showcasing the effectiveness of infliximab in managing this complex condition. The positive results underscore the potential of biologic therapies in addressing inflammatory diseases, offering a new frontier in treatment.

Empowering Patients: Understanding the Benefits and Challenges of Biologic Therapies

This study highlights the importance of educating patients about the potential benefits and challenges associated with biologic therapies. Open communication between patients and healthcare providers is essential for informed decision-making, empowering individuals to actively participate in their treatment journey.

Dr. Camel's Conclusion

This study marks a pivotal moment in the treatment of spondyloarthropathy, much like a desert oasis appearing after a long and arduous journey. The discovery of infliximab's efficacy offers a new path to improved health and well-being for those battling this challenging condition. It's a reminder that scientific innovation and collaboration can pave the way for transformative advancements in healthcare.

Date :
  1. Date Completed 2003-10-08
  2. Date Revised 2019-11-07
Further Info :

Pubmed ID

12951862

DOI: Digital Object Identifier

10.1016/s0889-857x(03)00052-8

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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