Paper Details
- Home
- Paper Details
The effects of the COMT inhibitor entacapone on haemodynamics and peripheral catecholamine metabolism during exercise.
Author: AkkilaJ, GordinA, IlliA, KeränenT, ScheininM, SundbergS
Original Abstract of the Article :
1. Catechol-O-methyltransferase (COMT) inhibition might be assumed to potentiate the effects of circulating catecholamines, particularly under conditions of enhanced catecholamine release. 2. The purpose of the present study was to establish whether the novel COMT inhibitor, entacapone, changes haem...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元：
https://doi.org/10.1111/j.1365-2125.1993.tb00394.x
データ提供：米国国立医学図書館（NLM）
The Impact of COMT Inhibition on Catecholamine Metabolism During Exercise
The [Role of catecholamines] in [Exercise] is a complex and fascinating area of [Physiology]. This study investigates the [Effects] of the [COMT inhibitor entacapone] on [Hemodynamics and peripheral catecholamine metabolism] during [Exercise]. This [Clinical trial] aimed to assess the [Impact of entacapone] on [Catecholamine levels and metabolism] during [Submaximal exercise]. The study found that [Entacapone] did not [Alter hemodynamics] but [Increased the levels of monoamine oxidase-dependent metabolites]. This study sheds light on the [Role of COMT inhibition] in [Catecholamine metabolism] during [Exercise].
Exploring the Desert of Catecholamine Metabolism: The Impact of COMT Inhibition
This study ventures into the [Desert of exercise physiology] to uncover the [Effects] of [COMT inhibition] on [Catecholamine metabolism]. The researchers discovered that [Entacapone] does not [Alter hemodynamics] but has a [Significant impact] on [Catecholamine metabolism], leading to [Increased levels of monoamine oxidase-dependent metabolites]. This research provides valuable insights into the [Complex interplay] between [COMT inhibition] and [Catecholamine metabolism] during [Exercise].
Understanding the Body's Response to Exercise: The Role of COMT Inhibition
This research reminds us of the [Intricate mechanisms] that govern our [Body's response to exercise]. The [Findings] suggest that [COMT inhibition] can [Influence catecholamine metabolism] in a way that [Enhances the effects] of [Monoamine oxidase]. While this study offers [Valuable insights], [Further research] is needed to fully understand the [Implications] of these findings for [Human health and performance].
Dr.Camel's Conclusion
This study investigates the effects of the COMT inhibitor entacapone on hemodynamics and peripheral catecholamine metabolism during exercise, revealing that entacapone does not alter hemodynamics but significantly influences catecholamine metabolism. The study highlights the complex interplay between COMT inhibition and catecholamine metabolism during exercise, providing valuable insights into the body's response to physical activity.
Date :
- Date Completed 2003-09-17
- Date Revised 2019-05-13
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.