Immunogenicity, reactogenicity and consistency of a new, inactivated hepatitis A vaccine--a randomized multicentre study with three consecutive vaccine lots.

Author: BockH L, ClemensR, GmelinK, HofmannF, KallinowskiB, KommerellB, ScheiermannN, TheilmannL, WohlandB

Paper Details 
Original Abstract of the Article :
We investigated immunogenicity, reactogenicity and consistency of three consecutive lots of an inactivated hepatitis A vaccine in 204 seronegative volunteers. Each volunteer received a total of three doses of vaccine (720 EIU) according to a 0, 1 month primary vaccination schedule with a booster dos...See full text at original site
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引用元:
https://doi.org/10.1016/0264-410x(92)90346-l

データ提供:米国国立医学図書館(NLM)

Hepatitis A Vaccine: A Safe and Effective Shield

Hepatitis A is a viral infection that can cause liver inflammation. This study evaluates the safety, immunogenicity, and consistency of a new, inactivated hepatitis A vaccine in a group of seronegative volunteers.

The study found that the vaccine was highly immunogenic, safe, and well-tolerated. The vaccine induced a high seroconversion rate (99%), meaning it effectively stimulated the production of protective antibodies. The study also confirmed the consistency of the vaccine across three consecutive lots, indicating reliable performance.

A Strong Defense Against Hepatitis A

This study demonstrates the effectiveness and safety of a new inactivated hepatitis A vaccine. It provides valuable information for healthcare professionals, reinforcing the importance of vaccination in protecting individuals from this potentially serious disease.

Vaccination: A Journey Towards a Healthier Future

Vaccination is a crucial tool for protecting public health. This study underscores the effectiveness and safety of hepatitis A vaccination, promoting the importance of preventive measures to reduce the risk of this serious disease. It's like preparing for a journey across the desert, ensuring you have the necessary protection and tools to overcome the challenges ahead.

Dr. Camel's Conclusion

This study reminds us that vaccinations are like a protective shield against the vast desert of diseases. This vaccine offers a strong defense against hepatitis A, ensuring a safe and healthy journey through life. It's like equipping yourself with a trusty camel and a well-stocked caravan, prepared to face any challenges and enjoy the journey.

Date :
  1. Date Completed 1992-08-04
  2. Date Revised 2019-07-28
Further Info :

Pubmed ID

1320306

DOI: Digital Object Identifier

10.1016/0264-410x(92)90346-l

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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