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Placebo-controlled efficacy study of hepatitis A vaccine in Valdivia, Chile.
Author: FrösnerG G, GonzalezJ L, HeringV, IbarraH, LeonJ, MoraledaL, ReinhardtG, RiedemannS, SiegelF, ToledoC
Original Abstract of the Article :
A placebo-controlled, double-blind study on the efficacy of a hepatitis A vaccine (SmithKline Beecham Biologicals) was started in a region of Chile in September 1990, using hepatitis B vaccine as control. A total of 260 healthy children, 6-15 years of age, negative for antibody to hepatitis A virus ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/0264-410x(92)90573-3
データ提供:米国国立医学図書館(NLM)
A Vaccine for Hepatitis A: A Step Towards Prevention
Hepatitis A, a viral infection that can cause liver inflammation, remains a public health concern worldwide. This study investigates the efficacy of a hepatitis A vaccine in a Chilean population, focusing on its ability to induce protective antibodies against the virus. The authors conducted a placebo-controlled, double-blind trial involving 260 healthy children, 6-15 years of age, who were randomly assigned to receive either the hepatitis A vaccine or a control vaccine. The results demonstrate a high rate of seroconversion (antibody development) in the vaccinated group, indicating the effectiveness of the vaccine in preventing hepatitis A infection.
Effective Protection Against Hepatitis A
This study provides strong evidence supporting the effectiveness of the hepatitis A vaccine in preventing infection. The high seroconversion rate observed in the vaccinated group highlights the significant impact of vaccination on public health, particularly in regions with a high prevalence of hepatitis A.
Staying Safe: Vaccination is Key
Vaccination remains the most effective way to prevent hepatitis A. This study emphasizes the importance of ensuring widespread access to vaccination programs, particularly for vulnerable populations, to reduce the incidence of this potentially serious disease. Regular hand washing and proper hygiene practices are also crucial for preventing the spread of hepatitis A.
Dr.Camel's Conclusion
Just like a camel navigating through a scorching desert, hepatitis A can pose a serious threat to health. This study highlights the power of vaccination as a shield against this viral infection, offering a beacon of hope for a healthier future. By embracing vaccination and practicing sound hygiene habits, we can effectively combat hepatitis A and create a safer environment for all.
Date :
- Date Completed 1993-02-01
- Date Revised 2019-07-28
Further Info :
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