Timolol-pilocarpine fixed-ratio combinations in the treatment of chronic open angle glaucoma. A controlled multicenter study of 48 weeks. Scandinavian Timpilo Study Group.

Author: PuustjärviT J, RepoL P

Paper Details 
Original Abstract of the Article :
The effect of the fixed combination of 0.5% timolol maleate with 2% pilocarpine hydrochloride given twice a day and 0.5% timolol with 4% pilocarpine given twice a day was tested in a long-term, multicenter study. A total of 360 patients with open angle glaucoma were included; they were defined as th...See full text at original site
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引用元:
https://doi.org/10.1001/archopht.1992.01080240065032

データ提供:米国国立医学図書館(NLM)

Timolol-Pilocarpine Combinations: A Double-Edged Sword for Glaucoma

Glaucoma, a condition that can feel like a slow erosion of vision, is a persistent threat to eye health. This study explores the effectiveness of combining timolol and pilocarpine, two common glaucoma medications, like combining different tools to navigate a challenging desert terrain.

Timolol-Pilocarpine: A Promising Combination for Glaucoma

This study demonstrates the efficacy of combining timolol and pilocarpine in lowering intraocular pressure in patients with open-angle glaucoma. It's like finding a more effective tool for clearing a path through a dense desert. The study found that the combination of timolol and pilocarpine was effective in lowering intraocular pressure, particularly in those who did not achieve adequate control with single-agent therapy. The researchers noted that the combination was generally well-tolerated, with few side effects.

Glaucoma: Navigating a Complex Terrain

The study highlights the potential benefits of combining timolol and pilocarpine, offering a new approach to managing glaucoma. It's like discovering a new path through the desert, potentially leading to better outcomes for patients. However, it also emphasizes the importance of careful monitoring and individualization of treatment, as with any medication, particularly in a complex condition like glaucoma.

Dr.Camel's Conclusion

This study offers a glimpse into the potential of combining timolol and pilocarpine for glaucoma management. It's like finding a new oasis in the desert of eye health, offering a potential solution to a challenging condition. However, it's essential to remember that every patient's journey is unique and requires careful navigation.
Date :
  1. Date Completed 1993-01-08
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

1342582

DOI: Digital Object Identifier

10.1001/archopht.1992.01080240065032

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English

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