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[Contribution of zolpidem in the management of sleep disorders].

Author: BenavidesJ, LavoisyJ, PerraultG H, RobertP, ZivkovicB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Zolpidem, a nonbenzodiazepine hypnotic, effectively improved sleep onset latency, reduced awakenings, and increased total sleep time. It had minimal impact on sleep architecture and showed a lower potential for tolerance and dependence than benzodiazepines.
Paper Details　
Original Abstract of the Article :
Zolpidem is a nonbenzodiazepine hypnotic agent belonging to a new class of psychotropic drugs the imidazopyridines which enhance the GABAA receptor function by interacting with a specific receptor population. Zolpidem binds selectively to the Omega-1 receptor subtype and from a pharmacological point...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1363657

データ提供：米国国立医学図書館（NLM）

Zolpidem: A Selective Hypnotic for Insomnia

Insomnia, a pervasive sleep disorder, can significantly impact an individual's quality of life. This study examines the effectiveness of zolpidem, a non-benzodiazepine hypnotic agent, in the management of sleep disorders. Zolpidem, belonging to the imidazopyridine class of drugs, interacts selectively with the GABA-A receptor, enhancing its function. The study highlights zolpidem's strong sedative and hypnotic properties, demonstrating its ability to reduce sleep onset latency, nocturnal awakenings, and increase total sleep time. Notably, zolpidem does not significantly alter sleep architecture, unlike traditional benzodiazepines. This research provides valuable insights into the efficacy and safety of zolpidem as a treatment option for insomnia, offering a potential alternative to traditional benzodiazepine hypnotics.

Zolpidem: A Safe and Effective Treatment for Insomnia

The study's findings suggest that zolpidem is a safe and effective treatment for insomnia, offering a potential alternative to traditional benzodiazepines. Its selective hypnotic properties, along with its minimal impact on sleep architecture, make it a promising option for patients seeking to improve their sleep quality without experiencing the undesirable side effects associated with traditional benzodiazepines.

A Better Night's Sleep: Choosing the Right Hypnotic

Imagine the joy of waking up refreshed and energized after a night of restful sleep. This research offers a new avenue to achieve that goal. By understanding the unique properties of zolpidem and other hypnotics, individuals can make informed decisions about their sleep health, choosing the most appropriate treatment option for their specific needs.

Dr.Camel's Conclusion

Insomnia can feel like a long, sleepless night in the desert, where the darkness seems to stretch endlessly. Zolpidem, with its targeted action and minimal side effects, offers a respite from the relentless heat and dryness of insomnia. It's like discovering a hidden oasis, providing a refreshing escape from the discomfort and fatigue of sleep deprivation. This research highlights the power of scientific innovation to provide solutions for those seeking a peaceful and restful night's sleep.

Date :
  1. Date Completed 1993-05-06
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

1363657

DOI: Digital Object Identifier

1363657

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・Effects of ulipristal・Effects of zolpidem
SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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