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Alendronate has a residual effect on bone mass in postmenopausal Danish women up to 7 years after treatment withdrawal.

Author: AlexandersenPeter, BaggerYu Z, ChristiansenClaus, RavnPernille, TankóLászló B

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Alendronate, a drug used to treat osteoporosis, has been shown to increase bone mineral density and reduce bone turnover. This study found that the beneficial effects of alendronate last for up to 7 years after treatment stops, and the rate of bone loss after stopping treatment is comparable to the normal rate of bone loss in postmenopausal women.
Paper Details　
Original Abstract of the Article :
Alendronate has been shown to reduce bone turnover and increase bone mass. However, little is known about the duration of the effect on bone after treatment withdrawal. The aim of this study was to investigate the long-term effects on bone mineral density (BMD) and bone turnover of various alendrona...See full text at original site
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引用元：
https://doi.org/10.1016/s8756-3282(03)00112-1

データ提供：米国国立医学図書館（NLM）

Alendronate: Long-term Effects on Bone Mass

Think of your bones as the pillars supporting a grand desert palace. As we age, these pillars can become weakened, making the palace more vulnerable to collapse. This study delves into the long-term effects of alendronate, a medication commonly used to treat osteoporosis, on bone mass in postmenopausal women. The researchers followed a group of women who had previously received alendronate treatment and compared them to a control group who did not receive treatment. They found that alendronate had a lasting impact on bone density, even after treatment was stopped, which is like strengthening the pillars of the desert palace, preventing it from crumbling even after the construction crew has left. This suggests that alendronate can have a long-term benefit in preventing bone loss.

Alendronate: A Lasting Impact on Bone Health

This study underscores the long-term benefits of alendronate in preventing bone loss. The researchers found that alendronate had a lasting impact on bone density, even after treatment was stopped, suggesting that it can provide long-term protection against osteoporosis. This is encouraging news, as it emphasizes the importance of ongoing bone health management, especially in postmenopausal women.

Maintaining Bone Strength: A Lifelong Journey

This research emphasizes the importance of maintaining bone health throughout life. Just as a desert traveler needs to be prepared for the long journey ahead, it's crucial to take steps to protect our bones, especially as we age. This study highlights the potential benefits of alendronate in preventing bone loss and promoting long-term bone health.

Dr.Camel's Conclusion

This study provides valuable insights into the long-term effects of alendronate on bone health. It's like discovering that a well-built desert palace can withstand the test of time, even after the construction crew has moved on. This research reminds us that maintaining bone strength is a lifelong journey, and alendronate can be a powerful tool in preventing bone loss and ensuring a strong foundation for the future.

Date :
  1. Date Completed 2004-05-26
  2. Date Revised 2019-09-06
Further Info :

Pubmed ID

13678770

DOI: Digital Object Identifier

10.1016/s8756-3282(03)00112-1

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Languages

English

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