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Low-dose radiation therapy and reduced chemotherapy in childhood Hodgkin's disease: the experience of the French Society of Pediatric Oncology.

Author: BertrandY, BeyP, ChompretA, HabrandJ L, LevergerG, OberlinO, PacquementH, RaquinM A, RubieH, Terrier-LacombeM J

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
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Overview

Reduced chemotherapy and radiation therapy regimens were investigated in children with Hodgkin's disease. ABVD regimen showed favorable results and low-dose radiation therapy proved effective after a good response to chemotherapy.
Paper Details　
Original Abstract of the Article :
With the aim of decreasing undesirable side effects of therapy, we investigated the reduction of both chemotherapy and radiation therapy (RT) in children with Hodgkin's disease, and compared Adriamycin (doxorubicin; Farmitalia Carlo Erba, Rueil-Malmaison, France), bleomycin, vinblastine, and dacarba...See full text at original site
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引用元：
https://doi.org/10.1200/JCO.1992.10.10.1602

データ提供：米国国立医学図書館（NLM）

Low-Dose Radiation Therapy and Reduced Chemotherapy in Childhood Hodgkin's Disease

Hodgkin's disease, a type of cancer affecting the lymphatic system, can be a challenging desert to navigate, requiring aggressive treatments that can have significant side effects. This study explores the potential of reducing both chemotherapy and radiation therapy (RT) in children with Hodgkin's disease, seeking to minimize the burden of treatment while maintaining effectiveness. The researchers found that reducing both chemotherapy and RT, particularly in favorable cases, could be a viable approach, potentially reducing the long-term side effects of treatment without compromising outcomes.

Reduced Therapy for Childhood Hodgkin's Disease: A More Gentle Desert Journey

This study suggests that reducing both chemotherapy and RT in children with Hodgkin's disease, particularly in favorable cases, could be a viable approach, potentially reducing the long-term side effects of treatment without compromising outcomes. The researchers found that low-dose RT after a good response to chemotherapy was effective in managing the disease.

Navigating the Desert of Childhood Cancer Treatment

This study underscores the importance of individualized approaches to childhood cancer treatment, recognizing the unique needs of each child. The researchers highlight the potential of reducing the intensity of treatment in favorable cases, potentially minimizing the long-term side effects while maintaining effectiveness.

Dr. Camel's Conclusion

This study explores a more gentle approach to treating childhood Hodgkin's disease, like finding a cooler path through a scorching desert. The researchers found that reducing both chemotherapy and RT, particularly in favorable cases, could be effective and reduce long-term side effects. This research offers hope for a less burdensome and more effective treatment approach for children battling Hodgkin's disease.

Date :
  1. Date Completed 1992-10-30
  2. Date Revised 2017-02-10
Further Info :

Pubmed ID

1383434

DOI: Digital Object Identifier

10.1200/JCO.1992.10.10.1602

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