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Comparison between cetirizine and terfenadine: time-response study.

Author: Olivé-PérezA, RandazzoL, ValenciaM

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Cetirizine 10mg showed a longer duration of peripheral antihistaminic effect than terfenadine 60mg. Both were well-tolerated and did not cause sedation or anticholinergic side effects.
Paper Details　
Original Abstract of the Article :
Six young healthy volunteers were used as experimental models to study the efficacy of cetirizine 10 mg and terfenadine 60 mg with regard to the onset of action and duration of the peripheral antihistaminic effect (cutaneous activity). For this purpose, 10 micrograms of histamine were used administe...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1384299

データ提供：米国国立医学図書館（NLM）

Comparing Cetirizine and Terfenadine: A Time-Response Study

The

allergic

response is like a camel's reaction to a sudden desert storm – a powerful and sometimes overwhelming response. This study investigates the efficacy and speed of action of two

antihistamines

,

cetirizine

and

terfenadine

, in blocking the histamine-induced reaction. The researchers wanted to see which drug was more effective and how long its effects lasted.

Cetirizine: A More Powerful Ally

The study found that both drugs were well-tolerated and did not cause significant side effects. However, cetirizine demonstrated a longer duration of action and a greater ability to block histamine's effects compared to terfenadine. This means that cetirizine might be a more effective choice for managing allergic reactions and providing longer-lasting relief.

Managing Allergies: A Desert Oasis of Relief

If you experience allergies, it's important to discuss your options with your doctor. They can help you determine the best treatment approach, considering your individual needs and allergies. Remember, just as a camel seeks refuge from the desert heat, finding the right medication can help you escape the discomfort of allergies.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of different antihistamines. While both cetirizine and terfenadine have their merits, cetirizine appears to offer a longer duration of action and potentially greater relief. Understanding the nuances of these drugs can help both doctors and patients find the best solution for managing allergies.

Date :
  1. Date Completed 1992-11-19
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

1384299

DOI: Digital Object Identifier

1384299

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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