[Effect of the captopril-hydrochlorothiazide combination on blood lipids. Study in a population of hypertensive hyperlipidemic patients].

Author: BuxtorfJ C, ClergeotA, JacototB, MeillardO, PiolotA, ProvendierO

Paper Details 
Original Abstract of the Article :
In this placebo-controlled, randomized double-blind, parallel study the effects of the fixed captopril 50 mg + hydrochlorothiazide (HCTZ) 25 mg combination on plasma lipids were assessed in 42 hypertensive, type IIa or IIb hyperlipidaemic patients on diets. Some patients received oral hypolipidaemic...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/1409461

データ提供:米国国立医学図書館(NLM)

Captopril-Hydrochlorothiazide: A Combination Therapy for Hypertension, But Not for Lipids

High blood pressure (hypertension) and high cholesterol (hyperlipidemia) are common health problems that can lead to cardiovascular disease. This study investigated the effects of a combination therapy of captopril and hydrochlorothiazide, a common treatment for hypertension, on lipid levels in patients with both hypertension and hyperlipidemia. The study included 42 patients who were randomly assigned to receive either the combination therapy or a placebo. The researchers found that the combination therapy effectively lowered blood pressure but had no significant effect on lipid levels. This suggests that the combination therapy is an effective treatment for hypertension but may not be the optimal choice for managing hyperlipidemia.

Hypertension Management: A Multi-Faceted Approach

This study highlights the importance of a tailored approach to managing chronic conditions like hypertension and hyperlipidemia. While the combination therapy showed effectiveness in lowering blood pressure, it did not influence lipid levels. This suggests that patients with both hypertension and hyperlipidemia may require a more comprehensive treatment plan, potentially including specific lipid-lowering medications in addition to the combination therapy.

A Holistic Approach to Cardiovascular Health

Managing cardiovascular health requires a holistic approach that considers both blood pressure and lipid levels. While this study demonstrates that the captopril-hydrochlorothiazide combination effectively manages blood pressure, it may not be sufficient for optimizing lipid levels. Consult with a healthcare professional to create a personalized treatment plan that addresses your specific needs and risk factors.

Dr. Camel's Conclusion

This study is a reminder that each patient is unique and requires a tailored treatment plan based on their individual needs and risk factors. Just like a desert ecosystem, our bodies are complex, and managing different health conditions requires a nuanced approach. In this case, while the combination therapy effectively addresses hypertension, it may not be enough to manage hyperlipidemia, highlighting the need for individualised treatments for optimal health.

Date :
  1. Date Completed 1992-10-29
  2. Date Revised 2016-12-09
Further Info :

Pubmed ID

1409461

DOI: Digital Object Identifier

1409461

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SNS
PICO Info
in preparation
Languages

French

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