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Carcinoma of the pancreas and papilla of Vater--assessment of resectability and factors influencing resectability in stage I carcinomas. A prospective multicentre trial in 472 patients.

Author: ArnesjøB, BakkevoldK E, KambestadB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A study of 472 patients with pancreatic or papilla of Vater cancer found that only 29% of pancreatic tumors and 89% of papillar tumors were resectable. The most effective diagnostic methods for identifying resectable tumors were fine needle aspiration cytology (FNAC) and endoscopic retrograde cholangiopancreatography (ERCP), while ultrasound had the lowest accuracy. Resectable tumors were generally smaller than unresectable tumors, and size increased with stage. The study concluded that exploratory laparotomy is often necessary to determine resectability in patients with pancreatic cancer, as current diagnostic methods are insufficient.
Paper Details　
Original Abstract of the Article :
Between 1984 and 1987, 472 patients with histologically or cytologically verified carcinomas of the pancreas or papilla of Vater, were accrued in the Norwegian Pancreatic Cancer Trial. Surgical assessment revealed resectability in 29% (94 of 330) of the pancreatic tumours and 89% (25 of 28) of the p...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/1426302

データ提供：米国国立医学図書館（NLM）

Carcinoma of the Pancreas and Papilla of Vater: Assessment of Resectability

This research delves into the complex world of pancreatic cancer, specifically focusing on its resectability. The study, a [prospective multicenter trial] involving [472 patients] with pancreatic or papillary tumors, aimed to assess the factors influencing the resectability of these tumors. The authors found that [29%] of pancreatic tumors and [89%] of papillary tumors were resectable. The study also investigated the accuracy of various diagnostic methods in determining resectability, highlighting the importance of careful pre-operative evaluation. The authors concluded that radical pancreatic surgery should only be undertaken if all diagnostic tests confirm resectability.

Factors Influencing Pancreatic Cancer Resectability

The study reveals that tumor size, presence of abdominal pain, and diagnostic delay are key factors influencing resectability. These findings emphasize the need for early detection and prompt evaluation of pancreatic tumors. The study shows that pancreatic cancer can be like a desert mirage – it can be difficult to detect and assess until it's too late. Early detection and timely intervention can make a significant difference in the outcome of the disease.

Importance of Early Detection in Pancreatic Cancer

This research highlights the importance of early detection in pancreatic cancer. The study demonstrates that prompt diagnosis and evaluation can significantly improve the chances of successful treatment. Early detection and intervention are crucial for navigating the harsh landscape of pancreatic cancer.

Dr. Camel's Conclusion

This study emphasizes the need for a multidisciplinary approach to the management of pancreatic cancer, including early detection, accurate diagnosis, and careful consideration of resectability. It's like navigating a vast and unforgiving desert – the right tools, skills, and early preparation are essential for survival.

Date :
  1. Date Completed 1992-12-04
  2. Date Revised 2007-07-02
Further Info :

Pubmed ID

1426302

DOI: Digital Object Identifier

1426302

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・Effective treatment of pancreatic cancer
SNS
PICO Info
in preparation
Languages

English

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