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Non-Hodgkin's lymphomas in children. II. Treatment.

Author: QuahT C, SiegelS E, WhiteL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

The prognosis of childhood non-Hodgkin's lymphoma (NHL) has improved with effective chemotherapy regimens tailored to prognostic categories. Surgery is beneficial only when near-total resection is possible. Radiation therapy is limited to specific situations. Intrathecal and systemic chemotherapy are effective for CNS lymphoma prevention. While lymphoblastic lymphoma has high cure rates, non-localized non-lymphoblastic disease remains challenging. Localized NHL has high cure rates with short chemotherapy regimens.
Paper Details　
Original Abstract of the Article :
The prognosis of non-Hodgkin's lymphoma (NHL) in childhood has improved steadily in the last 2 decades. This is primarily the result of increasingly effective chemotherapy regimens tailored to defined and relatively homogeneous prognostic categories and tested in prospective clinical trials. Surgica...See full text at original site
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引用元：
https://doi.org/10.1016/1040-8428(92)90017-k

データ提供：米国国立医学図書館（NLM）

Battling Non-Hodgkin's Lymphoma: A Comprehensive Approach

Non-Hodgkin's lymphoma (NHL), a type of cancer affecting the lymphatic system, can be a daunting challenge, especially in children. This research explores the evolving landscape of NHL treatment, focusing on the advancements made in the last two decades. The study delves into the efficacy of various treatment modalities, including chemotherapy, surgery, and radiation therapy, and highlights the importance of tailoring treatment regimens to specific subtypes of NHL and prognostic factors.

The Evolution of Treatment Strategies

The study underscores the significant improvements in NHL treatment outcomes over the past two decades, attributing this progress to increasingly effective chemotherapy regimens and individualized treatment approaches. The study also highlights the evolving role of surgery and radiation therapy, emphasizing their use in specific situations. This research, like a caravan adapting its route to navigate changing desert conditions, reflects the dynamic nature of medical practice, where new discoveries and advancements continually refine our understanding and approach to disease.

A Journey Towards Hope and Healing

The study's findings offer hope to children diagnosed with NHL. The advancements in treatment strategies, combined with the personalized approach, have significantly improved outcomes. Remember, my friends, that just as a desert oasis provides respite and nourishment to weary travelers, medical advancements offer hope and healing to those facing challenging health journeys.

Dr.Camel's Conclusion

This research provides a comprehensive overview of the evolving landscape of NHL treatment in children. The study highlights the advancements made in chemotherapy regimens, the evolving roles of surgery and radiation therapy, and the importance of personalized treatment approaches. This research, like a beacon guiding travelers through the complexities of disease, offers hope and direction in the battle against NHL.

Date :
  1. Date Completed 1993-01-07
  2. Date Revised 2019-10-28
Further Info :

Pubmed ID

1449620

DOI: Digital Object Identifier

10.1016/1040-8428(92)90017-k

Related Literature

Article Analysis
・Effective treatment of lymphoma
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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