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[A prospective study on rabeprazole-based triple therapy for Helicobacter pylori eradication in patients with peptic ulcer].

Author: ChoiBong Ki, ChungJung Myung, JangYoun Sik, LeeSang Hyuk, LeeYoun Jae, ParkEun Taek, SeolSang Young, YangSung Yeun

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

This study investigated the efficacy and safety of a one-week triple therapy regimen including rabeprazole for the eradication of Helicobacter pylori in patients with peptic ulcer disease. The study found that the eradication rate was 74.71% by intention-to-treat analysis and 87.84% by per-protocol analysis. The treatment was also well-tolerated, with only 12.5% of patients experiencing mild side effects.
Paper Details　
Original Abstract of the Article :
BACKGROUND/AIMS: Rabeprazole sodium is a potent proton pump inhibitor. We assessed the efficacy, safety and compliance of one-week triple therapy including rabeprazole with amoxicillin and clarithromycin for eradication of Helicobacter pylori (H. pylori). METHODS: Eighty-eight H. pylori-positive pa...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/14532713

データ提供：米国国立医学図書館（NLM）

Eradicating Helicobacter pylori: A One-Week Triple Therapy Approach

Helicobacter pylori, a bacteria that infects the stomach, can cause a variety of gastrointestinal problems, including peptic ulcers. Like a persistent desert wind, H. pylori can cause irritation and damage to the stomach lining.

This research investigates the efficacy of a one-week triple therapy regimen, including rabeprazole, amoxicillin, and clarithromycin, for eradicating H. pylori infection in patients with peptic ulcer disease. The researchers aimed to assess the effectiveness, safety, and compliance of this regimen.

The study found that the one-week triple therapy regimen was highly effective in eradicating H. pylori infection, with an eradication rate of 74.71% by intention-to-treat analysis and 87.84% by per-protocol analysis. The therapy was also well-tolerated, with a low incidence of side effects.

One-Week Triple Therapy: A Convenient and Effective Approach

This research highlights the efficacy and convenience of a one-week triple therapy regimen for eradicating H. pylori infection. Its shorter duration and effectiveness make it a promising approach for managing this common gastrointestinal infection.

Navigating the Desert of H. pylori Infection: Understanding Treatment Options

The desert of H. pylori infection can be a challenging landscape to navigate. This research provides valuable information about the effectiveness of a one-week triple therapy regimen, offering a convenient and effective approach to treating this infection.

Dr. Camel's Conclusion

This research underscores the effectiveness and convenience of a one-week triple therapy regimen for eradicating H. pylori infection. It offers a promising approach to managing this common gastrointestinal infection, providing a shorter treatment duration without compromising efficacy. Remember, like a seasoned desert traveler, we must seek the most efficient and effective methods to address our health concerns.
Date :
  1. Date Completed 2004-04-15
  2. Date Revised 2020-12-08
Further Info :

Pubmed ID

14532713

DOI: Digital Object Identifier

200308102

Related Literature

Article Analysis
・Side Effects of rabeprazole
SNS
PICO Info
in preparation
Languages

Korean

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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