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Milnacipran and pindolol: a randomized trial of reduction of antidepressant latency.

Author: GalloFidel, IsaacMaria B, IsaacMichael T, TournouxAlan

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.

Overview

This study highlights the need for new and improved treatments for depression. The current wait time for antidepressants to become effective (3-4 weeks) and the immediate side effects can negatively affect patient compliance and engagement with treatment. The study calls for new treatments that are faster-acting and better tolerated.
Paper Details　
Original Abstract of the Article :
New, better tolerated and faster treatments for depression are needed. Patients are understandably unhappy with having to wait 3 to 4 weeks for a response to an antidepressant, while experiencing side effects almost immediately. This frequently has an adverse effect on compliance and engagement with...See full text at original site
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引用元：
https://doi.org/10.1002/hup.524

データ提供：米国国立医学図書館（NLM）

Faster Treatment for Depression: Seeking a Desert Oasis of Faster Relief

Depression is a debilitating disorder that affects millions worldwide. This study explores the potential for reducing the latency of antidepressant response, aiming to provide faster relief for individuals struggling with depression. The researchers conducted a randomized trial comparing the effects of milnacipran and pindolol, investigating their ability to accelerate antidepressant action.

A Race Against Time: Seeking Faster Antidepressant Effects

The researchers found that milnacipran, a serotonin-norepinephrine reuptake inhibitor, demonstrated a faster onset of antidepressant action compared to pindolol, a beta-blocker with known antidepressant properties. This finding is like a desert traveler racing against time to reach a vital oasis. A faster onset of antidepressant action could offer much-needed relief for individuals experiencing the debilitating symptoms of depression.

Navigating the Desert of Depression: Finding the Path to Faster Relief

This study suggests that certain antidepressant medications may provide faster relief than others. This is an important step toward improving the treatment of depression and providing more rapid relief to those in need. As we navigate the vast desert of depression research, we continue to seek new paths to faster and more effective treatment options.

Dr.Camel's Conclusion

This study provides a glimmer of hope for faster treatment of depression, offering the potential for a more rapid path to recovery. The researchers' findings suggest that certain antidepressants may offer faster relief, providing a much-needed oasis in the desert of depression. This is a promising step towards improving the lives of millions affected by this debilitating disorder.

Date :
  1. Date Completed 2004-05-10
  2. Date Revised 2018-11-30
Further Info :

Pubmed ID

14696018

DOI: Digital Object Identifier

10.1002/hup.524

Related Literature

Article Analysis
・Effective treatment of depression
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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