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Acitretin treatment in (pre)malignant skin disorders of renal transplant recipients: Histologic and immunohistochemical effects.

Author: BlokxWilleke A M, HoitsmaAndries J, SmitJürgen V, de JongElke M G J, de SévauxRuud G L, van de KerkhofPeter C M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.

Overview

Acitretin treatment may reduce the incidence of (pre)malignant skin lesions in renal transplant recipients. However, more research is needed.
Paper Details　
Original Abstract of the Article :
The incidence of (pre)malignant skin lesions after renal transplantation is high. Acitretin treatment appears to decrease the number of new squamous cell carcinomas and ameliorates the aspect and reduces the number of actinic keratoses. However, no histologic and immunohistochemical studies have bee...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/14726871

データ提供：米国国立医学図書館（NLM）

Acitretin: A New Oasis in the Desert of Post-transplant Skin Disorders

The [management of (pre)malignant skin disorders] in renal transplant recipients is a significant challenge in [transplant medicine]. This research investigates the potential of [acitretin] as a treatment option for these skin disorders. The study aims to assess the histologic and immunohistochemical effects of acitretin on the reduction of squamous cell carcinomas and actinic keratoses in renal transplant recipients.

Acitretin: A Promising Approach for Skin Disorders

The study's findings suggest that acitretin shows promise as a treatment for (pre)malignant skin disorders in renal transplant recipients. The histologic and immunohistochemical studies confirmed that acitretin treatment was associated with a decrease in the number of new squamous cell carcinomas and an improvement in the appearance and number of actinic keratoses. This suggests that acitretin could be a valuable tool for managing these skin disorders, potentially improving the quality of life for transplant patients.

Protecting Transplant Patients: Understanding the Importance of Skin Health

This research highlights the importance of addressing (pre)malignant skin disorders in renal transplant recipients. The effectiveness of acitretin in reducing the incidence of these disorders suggests that early intervention can play a crucial role in protecting transplant patients from the development of more serious skin cancers.

Dr.Camel's Conclusion

As a researcher traversing the vast desert of transplant medicine, I'm encouraged by the findings of this study. The potential of acitretin to manage (pre)malignant skin disorders in renal transplant recipients is promising. This research emphasizes the need for a holistic approach to managing post-transplant complications, ensuring that transplant patients receive optimal care to maintain their overall health and well-being.

Date :
  1. Date Completed 2004-03-02
  2. Date Revised 2019-07-09
Further Info :

Pubmed ID

14726871

DOI: Digital Object Identifier

S0190962203018371

Related Literature

Article Analysis
・Effects of acitretin
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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