Effect of high-dose fluticasone propionate on bone density and metabolism in children with asthma.

Author: ArmstrongDavid, FreezerNicholas, GriffithsAmanda L, RoddaChristine, SimDerrick, StraussBoyd

Paper Details 
Original Abstract of the Article :
Significant concern remains over the long-term side effects of inhaled steroids. This cross-sectional study evaluates the effect of high-dose inhaled fluticasone propionate (FP) on biochemical markers of bone metabolism and bone density in children with asthma. Children with chronic asthma using FP ...See full text at original site
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引用元:
https://doi.org/10.1002/ppul.10396

データ提供:米国国立医学図書館(NLM)

Inhaled Steroids and Bone Health: A Closer Look in Children with Asthma

Inhaled steroids, a mainstay in asthma management, have been a source of concern due to potential long-term side effects. This study examines the impact of high-dose inhaled fluticasone propionate (FP) on bone density and metabolism in children with asthma. The researchers aimed to address the question of whether prolonged use of high-dose inhaled steroids could negatively impact bone health in this vulnerable population.

Inhaled Steroids: Balancing Asthma Control and Bone Health

The study, conducted on a group of children with asthma using high doses of FP, revealed no significant difference in biochemical markers of bone metabolism compared to healthy controls. However, a subgroup of children with asthma showed a reduced lumbar spine density, raising concerns about potential bone health implications. This study provides valuable data on the long-term effects of inhaled steroids in children with asthma, highlighting the need for careful monitoring of bone health and individualized treatment approaches to balance asthma control and minimize potential side effects.

Navigating the Tightrope Between Asthma Management and Bone Health

This study, like a desert traveler navigating a precarious path, explores the delicate balance between asthma management and bone health in children. While high-dose inhaled steroids effectively control asthma symptoms, they may have subtle effects on bone density. This research underscores the importance of individualized treatment plans and regular monitoring of bone health to ensure optimal outcomes for children with asthma.

Dr.Camel's Conclusion

Imagine inhaled steroids as a refreshing oasis in the desert of asthma symptoms, offering relief and control. However, prolonged exposure to these therapeutic oases might have subtle effects on bone health, like the subtle shifts in a desert landscape over time. This study, like a careful desert explorer, highlights the need to balance the benefits and potential risks of inhaled steroids, ensuring optimal outcomes for children with asthma.

Date :
  1. Date Completed 2004-06-24
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

14730656

DOI: Digital Object Identifier

10.1002/ppul.10396

Related Literature

SNS
PICO Info
in preparation
Languages

English

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